RAB11FIP2 and MYO5B

Number of citations of the paper that reports this interaction (PubMedID 11495908)
118

Data Source:
HPRD (in vivo, in vitro, two hybrid)

		RAB11FIP2	MYO5B
Description		RAB11 family interacting protein 2	myosin VB
Image
GO Annotations	Cellular Component	Phagocytic Cup Cell Nucleoplasm Endosome Cytoplasmic Vesicle Membrane Cell Projection Intracellular Membrane-bounded Organelle Recycling Endosome Membrane	Cytoplasm Actin Cytoskeleton Myosin Complex Cytoplasmic Vesicle Membrane Vesicle Protein-containing Complex Apical Cortex Recycling Endosome Extracellular Exosome
	Molecular Function	Protein Binding Rab GTPase Binding Protein Kinase Binding Identical Protein Binding Protein Homodimerization Activity	Microfilament Motor Activity Protein Binding Calmodulin Binding ATP Binding Rab GTPase Binding Actin-dependent ATPase Activity Actin Filament Binding
	Biological Process	Renal Water Homeostasis Phagocytosis Establishment Of Cell Polarity TRAM-dependent Toll-like Receptor 4 Signaling Pathway Insulin Secretion Involved In Cellular Response To Glucose Stimulus Positive Regulation Of GTPase Activity Regulated Exocytosis Positive Regulation Of Protein Localization To Plasma Membrane	Renal Water Homeostasis Actin Filament Organization Protein Transport Vesicle-mediated Transport Endosomal Transport Vesicle Transport Along Actin Filament
Pathways		Vasopressin regulates renal water homeostasis via Aquaporins	Vasopressin regulates renal water homeostasis via Aquaporins
Drugs
Diseases
GWAS		Age spots ( 29895819) Asthma (sex interaction) ( 24824216) Celiac disease ( 23936387) Freckles ( 29895819) Homeostasis model assessment of beta-cell function (dietary factor interaction) ( 24204828) Serum uric acid levels ( 30993211 29403010)	Apolipoprotein A1 levels ( 29084231) Large HDL particle concentration ( 29084231) Mean diameter of HDL particles ( 29084231) Medium HDL particle concentration ( 29084231) Multiple sclerosis ( 31604244) Myopia ( 27182965) Phospholipid levels in large HDL ( 29084231) Phospholipid levels in medium HDL ( 29084231) Resistant hypertension ( 31545351) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Systolic blood pressure x smoking status (current vs non-current) interaction (1df test) ( 29455858) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Total cholesterol levels in HDL ( 29084231)
Interacting Genes		14 interacting genes: AP2A1 CXCR2 EHD1 ITSN1 LRRK2 MARK2 MYO5B PDZD11 RAB11A RAB11B RAB11FIP4 RAB25 REPS1 YWHAG	13 interacting genes: AMOTL2 BNIP2 COIL CXCR2 KIAA1549 POLR1C RAB11A RAB11B RAB11FIP2 RAB25 SMAD3 TCF4 TRIM54
Entrez ID		22841	4645
HPRD ID		10548	07582
Ensembl ID		ENSG00000107560	ENSG00000167306
Uniprot IDs		Q7L804	Q7Z7A5 Q9ULV0
PDB IDs		2GZD 2GZH 2K6S 3TSO 4C4P	4J5M 4LNZ 4LWZ 4LX0
Enriched GO Terms of Interacting Partners?
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