RPGRIP1 and GATAD2B

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		RPGRIP1	GATAD2B
Description		RPGR interacting protein 1	GATA zinc finger domain containing 2B
Image			No pdb structure
GO Annotations	Cellular Component	Axoneme Photoreceptor Connecting Cilium	Nuclear Chromatin Nucleoplasm NuRD Complex Nuclear Speck Protein-containing Complex
	Molecular Function	Protein Binding	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding Protein Binding Zinc Ion Binding Nucleosomal DNA Binding
	Biological Process	Visual Perception Eye Photoreceptor Cell Development Response To Stimulus Retina Development In Camera-type Eye Neural Precursor Cell Proliferation	Negative Regulation Of Transcription By RNA Polymerase II ATP-dependent Chromatin Remodeling
Pathways			HDACs deacetylate histones ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression Regulation of TP53 Activity through Acetylation RNA Polymerase I Transcription Initiation Regulation of PTEN gene transcription Regulation of PTEN gene transcription
Drugs
Diseases		Leber congenital amaurosis (LCR) Cone-rod dystrophy and cone dystrophy, including: Cone-rod dystrophy (CORD); Cone dystrophy (COD); Retinal cone dystrophy (RCD)
GWAS		Body mass index ( 26426971) Body mass index (age>50) ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971) Height ( 31562340) Superior temporal sulcus banks volume ( 31530798)	Age at first birth ( 27798627) Chronotype ( 30696823) Empathy quotient ( 29527006) General cognitive ability ( 29844566) Height ( 31562340) Lentiform nucleus volume ( 22903471) Number of children ever born ( 27798627)
Interacting Genes		26 interacting genes: AEN BRCA1 CBX8 CCDC146 CHCHD3 CSPP1 DPPA4 FAM74A4 FEM1C GATAD2B HEYL IQCE MAGEB2 NPHP4 PTF1A RNF6 RPGR RPP25L SCNM1 TBC1D7 TFPT TRIB3 ZNF337 ZNF417 ZNF564 ZNF688	20 interacting genes: CALCOCO2 CEP70 GOLGA2 H2AC20 H2BC21 H3C1 H4C1 KAT2B MBD2 MBD3 MTNR1A PRKAB2 RBPMS RPGRIP1 SMAD2 SUMO2 TEX11 TRAF1 TRIM27 USHBP1
Entrez ID		57096	57459
HPRD ID		05673	15094
Ensembl ID		ENSG00000092200	ENSG00000143614
Uniprot IDs		Q96KN7	Q8WXI9
PDB IDs		4QAM
Enriched GO Terms of Interacting Partners?
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