FAM20C and PFDN1

Number of citations of the paper that reports this interaction (PubMedID 21900206)
114

Data Source:
BioGRID (two hybrid)

		FAM20C	PFDN1
Description		FAM20C golgi associated secretory pathway kinase	prefoldin subunit 1
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GO Annotations	Cellular Component	Extracellular Space Endoplasmic Reticulum Lumen Golgi Apparatus Extracellular Exosome	Prefoldin Complex
	Molecular Function	Protein Serine/threonine Kinase Activity Calcium Ion Binding Protein Binding ATP Binding Phosphotransferase Activity, Alcohol Group As Acceptor Manganese Ion Binding	DNA-binding Transcription Factor Activity Protein Binding Protein Binding Involved In Protein Folding Unfolded Protein Binding
	Biological Process	Protein Phosphorylation Phosphorylation Positive Regulation Of Bone Mineralization Biomineral Tissue Development Osteoclast Maturation Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Post-translational Protein Modification Cellular Protein Metabolic Process Positive Regulation Of Osteoblast Differentiation ATP Metabolic Process Regulation Of Phosphorus Metabolic Process Enamel Mineralization Odontoblast Differentiation Dentinogenesis	Regulation Of Transcription, DNA-templated Protein Folding
Pathways		Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation	Prefoldin mediated transfer of substrate to CCT/TriC
Drugs
Diseases		Raine syndrome; Lethal osteosclerotic bone dysplasia
GWAS		Allergic rhinitis ( 25085501) Alzheimer's disease in APOE e4- carriers ( 25778476)	Alzheimer's disease ( 28183528) Alzheimer's disease in APOE e4- carriers ( 25778476) Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Reaction time ( 29844566)
Interacting Genes		7 interacting genes: FAM118B PFDN1 SMN1 SUV39H2 TAF1D TK1 TSC22D1	53 interacting genes: ACTA1 ACTB ALB BRK1 CCDC85A CEP126 CHGA DCTN1 DEFA1 EDRF1 EIF3C EIF4A2 EOMES ESS2 EXT2 EZH2 FAM20C GET3 GIT1 GPRASP1 HAP1 HIP1 HMGXB3 HOXD8 IFT140 IMMT INPP5K JADE1 KIAA0408 LRIF1 MED31 NDC80 NR2F1 PDE4DIP PDHB PFDN2 PLXNB2 PRKD2 PSME1 PTN RMI1 RPLP1 RPS28 SEC31A SKP2 SNX5 SPTBN4 SUMO3 SYNDIG1 TERT TTC38 YEATS4 ZNF235
Entrez ID		56975	5201
HPRD ID		13298	05357
Ensembl ID		ENSG00000177706	ENSG00000113068
Uniprot IDs		Q8IXL6	O60925
PDB IDs		5YH3	6NR8 6NR9 6NRB 6NRC 6NRD
Enriched GO Terms of Interacting Partners?
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