PFDN1 and HOXD8

Number of citations of the paper that reports this interaction (PubMedID 21900206)
114

Data Source:
BioGRID (two hybrid)

		PFDN1	HOXD8
Description		prefoldin subunit 1	homeobox D8
Image			No pdb structure
GO Annotations	Cellular Component	Prefoldin Complex	Nuclear Chromatin Nucleus
	Molecular Function	DNA-binding Transcription Factor Activity Protein Binding Protein Binding Involved In Protein Folding Unfolded Protein Binding	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
	Biological Process	Regulation Of Transcription, DNA-templated Protein Folding	Negative Regulation Of Transcription By RNA Polymerase II Anterior/posterior Axis Specification, Embryo Positive Regulation Of Transcription By RNA Polymerase II Skeletal System Morphogenesis
Pathways		Prefoldin mediated transfer of substrate to CCT/TriC
Drugs
Diseases
GWAS		Alzheimer's disease ( 28183528) Alzheimer's disease in APOE e4- carriers ( 25778476) Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Reaction time ( 29844566)	Blood urea nitrogen levels ( 31152163) Chronic kidney disease ( 31152163) Estimated glomerular filtration rate ( 31152163 31015462 30604766) Glomerular filtration rate (creatinine) ( 28452372) Male-pattern baldness ( 28196072) Urate levels ( 31578528)
Interacting Genes		53 interacting genes: ACTA1 ACTB ALB BRK1 CCDC85A CEP126 CHGA DCTN1 DEFA1 EDRF1 EIF3C EIF4A2 EOMES ESS2 EXT2 EZH2 FAM20C GET3 GIT1 GPRASP1 HAP1 HIP1 HMGXB3 HOXD8 IFT140 IMMT INPP5K JADE1 KIAA0408 LRIF1 MED31 NDC80 NR2F1 PDE4DIP PDHB PFDN2 PLXNB2 PRKD2 PSME1 PTN RMI1 RPLP1 RPS28 SEC31A SKP2 SNX5 SPTBN4 SUMO3 SYNDIG1 TERT TTC38 YEATS4 ZNF235	5 interacting genes: ANXA7 CDKN1A HMGB1 PFDN1 RCC1
Entrez ID		5201	3234
HPRD ID		05357	00868
Ensembl ID		ENSG00000113068	ENSG00000175879
Uniprot IDs		O60925	A0A0A0MSX5 P13378
PDB IDs		6NR8 6NR9 6NRB 6NRC 6NRD
Enriched GO Terms of Interacting Partners?
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