NDUFA4L2 and EIF3C

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
HPRD (two hybrid)

		NDUFA4L2	EIF3C
Description		NDUFA4 mitochondrial complex associated like 2	eukaryotic translation initiation factor 3 subunit C
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrial Respiratory Chain Complex IV	Cytosol Eukaryotic Translation Initiation Factor 3 Complex Eukaryotic 43S Preinitiation Complex Eukaryotic 48S Preinitiation Complex
	Molecular Function	Cytochrome-c Oxidase Activity	RNA Binding Translation Initiation Factor Activity Protein Binding Translation Initiation Factor Binding Ribosome Binding
	Biological Process	Electron Transport Chain Proton Transmembrane Transport	Formation Of Cytoplasmic Translation Initiation Complex Translational Initiation Positive Regulation Of Translation Positive Regulation Of MRNA Binding
Pathways			L13a-mediated translational silencing of Ceruloplasmin expression Translation initiation complex formation Formation of a pool of free 40S subunits Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit
Drugs		NADH
Diseases
GWAS		Asthma ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Schizophrenia ( 25056061 29483656)	Crohn's disease ( 28067908 21102463) Extremely high intelligence ( 29520040) Inflammatory bowel disease ( 28067908 23128233) Inflammatory bowel disease (early onset) ( 19915574)
Interacting Genes		13 interacting genes: ANXA9 C6orf62 COMMD8 DYNLL1 EIF3C ERG28 KAT5 KCNA4 LUC7L2 PRKN QTRT1 SLC35F6 UBR1	17 interacting genes: AAGAB ALKBH4 BCKDK CALM1 EIF1AX EIF3E EIF3G EIF3J EIF3K HMOX2 MAPK6 NDUFA4L2 PFDN1 RPS6KA3 SMAD9 SNIP1 TACC3
Entrez ID		56901	8663
HPRD ID		14249	04889
Ensembl ID		ENSG00000185633	ENSG00000184110
Uniprot IDs		A0A024RB39 Q9NRX3	A0A024QYU9 Q99613
PDB IDs			3J8B 3J8C
Enriched GO Terms of Interacting Partners?
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