ANKS1B and RIN1

Number of citations of the paper that reports this interaction (PubMedID 25814554)
22

Data Source:
BioGRID (two hybrid)

		ANKS1B	RIN1
Description		ankyrin repeat and sterile alpha motif domain containing 1B	Ras and Rab interactor 1
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Plasma Membrane Postsynaptic Density Cajal Body Cell Junction Dendritic Spine Intracellular Membrane-bounded Organelle	Cytoplasm Cytosol Cytoskeleton Plasma Membrane Dendrite Neuronal Cell Body
	Molecular Function	Ephrin Receptor Binding	GTPase Activator Activity Protein Binding Ras GTPase Binding
	Biological Process	Regulation Of Synaptic Plasticity By Receptor Localization To Synapse	Endocytosis Signal Transduction Memory Associative Learning Negative Regulation Of Synaptic Plasticity Positive Regulation Of GTPase Activity
Pathways			RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
GWAS		Alcohol dependence or heroin dependence or methamphetamine dependence ( 31462767) Amyotrophic lateral sclerosis (age of onset) ( 22959728) Angiotensin-converting enzyme inhibitor intolerance ( 28030426) anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined) ( 23453885) Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Body fat percentage ( 31752434) Body mass index ( 20966902) Body mass index and waist-hip ratio (pleiotropy) ( 29868124) Electrodermal activity ( 25387706) Metabolite levels (HVA/5-HIAA ratio) ( 23319000) Obesity-related traits ( 23251661) Peak cortisol response to low dose short synacthen test in corticosteroid treated asthma ( 29551627) Response to antipsychotic treatment ( 19721433) Response to antipsychotic treatment in schizophrenia (working memory) ( 21107309) Response to methotrexate in juvenile idiopathic arthritis ( 24709693) Waist circumference ( 20966902)	Bipolar disorder ( 21926972 31043756)
Interacting Genes		9 interacting genes: APP EGFR ERBB2 ERBB4 HTR2A LRP1 LRP2 RIN1 UBC	19 interacting genes: ABL1 ABL2 AFDN ANKS1B CALCOCO2 EGFR ERBB2 ERBB3 HRAS KRTAP13-1 LZTS2 MTDH RAB5A RAB5B RALGDS RRAS2 YWHAB YWHAE YWHAZ
Entrez ID		56899	9610
HPRD ID		07426	05813
Ensembl ID		ENSG00000185046	ENSG00000174791
Uniprot IDs		B1VKB5 B7Z9I9 Q6V0K8 Q7Z6G8	A0A0S2Z4U0 Q13671
PDB IDs		2EAM 2KE7 2KIV 2M38
Enriched GO Terms of Interacting Partners?
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