PRTN3 and CAMP

Number of citations of the paper that reports this interaction (PubMedID 11389039)
195

Data Source:
HPRD (in vitro, in vivo)

		PRTN3	CAMP
Description		proteinase 3	cathelicidin antimicrobial peptide
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Cytosol Plasma Membrane Azurophil Granule Lumen Plasma Membrane Raft Collagen-containing Extracellular Matrix Extracellular Exosome	Extracellular Region Extracellular Space Specific Granule Lumen Specific Granule Extracellular Exosome Tertiary Granule Lumen
	Molecular Function	Serine-type Endopeptidase Activity Signaling Receptor Binding Protein Binding Serine-type Peptidase Activity Enzyme Binding	Lipopolysaccharide Binding
	Biological Process	Proteolysis Membrane Protein Ectodomain Proteolysis Phagocytosis Blood Coagulation Positive Regulation Of Cell Proliferation Cytokine-mediated Signaling Pathway Antimicrobial Humoral Response Collagen Catabolic Process Neutrophil Degranulation Positive Regulation Of GTPase Activity Cell-cell Junction Maintenance Negative Regulation Of Phagocytosis Neutrophil Extravasation Mature Conventional Dendritic Cell Differentiation	Innate Immune Response In Mucosa Antimicrobial Humoral Response Antibacterial Humoral Response Defense Response To Bacterium Neutrophil Degranulation Innate Immune Response Defense Response To Gram-negative Bacterium Defense Response To Gram-positive Bacterium Killing By Host Of Symbiont Cells Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide
Pathways		Common Pathway of Fibrin Clot Formation Other interleukin signaling Neutrophil degranulation Antimicrobial peptides	Neutrophil degranulation Antimicrobial peptides
Drugs		Elafin	Selenocysteine
Diseases
GWAS		Antineutrophil cytoplasmic antibody-associated vasculitis ( 28029757) Basophil percentage of granulocytes ( 27863252) Basophil percentage of white cells ( 27863252) Blood protein levels ( 30072576 29875488) Monocyte percentage of white cells ( 27863252) White blood cell count (basophil) ( 27863252)	Blood protein levels ( 30072576 28240269)
Interacting Genes		13 interacting genes: CAMP ELN F2R F2RL1 IL1B IL32 ITGB2 RELA SERPINA1 SERPINB1 SERPINB13 SMAD3 TNF	8 interacting genes: CTSG ELANE FPR2 GPX1 LBP MAPK8 PRTN3 RHOA
Entrez ID		5657	820
HPRD ID		01512	02722
Ensembl ID		ENSG00000196415	ENSG00000164047
Uniprot IDs		P24158	A0A384NPR0 J3KNB4 P49913
PDB IDs		1FUJ	2FBS 2FBU 2FCG 2K6O 2LMF 2NA3 4EYC 5NMN 5NNK 5NNM 5NNT 5XNG 5XRX 6BIV 6BIX
Enriched GO Terms of Interacting Partners?
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