PRTN3 and SERPINB1

Number of citations of the paper that reports this interaction (PubMedID 12114510)
12

Data Source:
HPRD (in vitro)

		PRTN3	SERPINB1
Description		proteinase 3	serpin family B member 1
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Cytosol Plasma Membrane Azurophil Granule Lumen Plasma Membrane Raft Collagen-containing Extracellular Matrix Extracellular Exosome	Extracellular Region Extracellular Space Membrane Secretory Granule Lumen Cytoplasmic Ribonucleoprotein Granule Collagen-containing Extracellular Matrix Extracellular Exosome
	Molecular Function	Serine-type Endopeptidase Activity Signaling Receptor Binding Protein Binding Serine-type Peptidase Activity Enzyme Binding	Serine-type Endopeptidase Inhibitor Activity Protein Binding Peptidase Inhibitor Activity
	Biological Process	Proteolysis Membrane Protein Ectodomain Proteolysis Phagocytosis Blood Coagulation Positive Regulation Of Cell Proliferation Cytokine-mediated Signaling Pathway Antimicrobial Humoral Response Collagen Catabolic Process Neutrophil Degranulation Positive Regulation Of GTPase Activity Cell-cell Junction Maintenance Negative Regulation Of Phagocytosis Neutrophil Extravasation Mature Conventional Dendritic Cell Differentiation	Negative Regulation Of Endopeptidase Activity Neutrophil Degranulation Type B Pancreatic Cell Proliferation Negative Regulation Of Interleukin-1 Beta Secretion
Pathways		Common Pathway of Fibrin Clot Formation Other interleukin signaling Neutrophil degranulation Antimicrobial peptides	Neutrophil degranulation
Drugs		Elafin
Diseases
GWAS		Antineutrophil cytoplasmic antibody-associated vasculitis ( 28029757) Basophil percentage of granulocytes ( 27863252) Basophil percentage of white cells ( 27863252) Blood protein levels ( 30072576 29875488) Monocyte percentage of white cells ( 27863252) White blood cell count (basophil) ( 27863252)	BMI at 5 years old ( 31575865) Cerebrospinal fluid AB1-42 levels ( 28247064)
Interacting Genes		13 interacting genes: CAMP ELN F2R F2RL1 IL1B IL32 ITGB2 RELA SERPINA1 SERPINB1 SERPINB13 SMAD3 TNF	3 interacting genes: ELANE PRTN3 XPO1
Entrez ID		5657	1992
HPRD ID		01512	00555
Ensembl ID		ENSG00000196415	ENSG00000021355
Uniprot IDs		P24158	P30740 V9HWH1
PDB IDs		1FUJ	4GA7
Enriched GO Terms of Interacting Partners?
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