HTRA1 and RPS6KA1

  • Number of citations of the paper that reports this interaction (PubMedID 30726710)
  • 1
  • Data Source:
  • BioGRID (unspecified method)

HTRA1

RPS6KA1

Description HtrA serine peptidase 1 ribosomal protein S6 kinase A1
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Advanced age-related macular degeneration ( 26691988)
  • Age-related macular degeneration ( 20385819 20385826 22694956 23326517 23455636 23536807 20861866 21665990)
  • Age-related macular degeneration (choroidal neovascularisation) ( 22705344)
  • Age-related macular degeneration (CNV vs. GA) ( 22705344)
  • Age-related macular degeneration (extreme sampling) ( 23577725)
  • Age-related macular degeneration (geographic atrophy) ( 22705344)
  • Age-related macular degeneration (wet) ( 17053108)
  • Coronary artery disease ( 29212778)
  • Disease progression in age-related macular degeneration ( 29346644)
  • Disease progression to choroidal neovascularization form in age-related macular degeneration ( 29346644)
  • Disease progression to geographic atrophy form in age-related macular degeneration ( 29346644)
  • Diverticular disease ( 30177863)
  • Exudative age-related macular degeneration ( 25629512)
  • Laterality in neovascular age-related macular degeneration ( 28775256)
  • Lung function (FEV1/FVC) ( 30061609 30804560)
  • Migraine ( 27322543)
  • Neovascular age-related macular degeneration ( 28703135)
  • Stroke ( 29531354)
  • Systolic blood pressure ( 30224653 30578418)
Interacting Genes 21 interacting genes: APOE BMP4 CAST CDYL COL1A1 COL2A1 COL3A1 COX5A CSNK2B FAM107A FCHSD2 GDF5 GOLGA2 IMPDH1 LRP10 MAPT NOS3 PARD6B RPS6KA1 TENT5A XIAP 86 interacting genes: ARHGEF11 ARHGEF12 ATXN3 BAD CARHSP1 CCT4 CDKN1B CEBPB CFL1 CREB1 CREBBP DDAH2 DEPTOR DLC1 DLG4 EEF1D EEF2K ERBIN ESR1 ETV1 FGFR1 FOS GBP2 GMFB GOPC GORASP1 GORASP2 GRB2 GRID2IP GSK3B HTRA1 L1CAM LIMK2 LNX1 MAGI1 MAGI2 MAGI3 MAPK1 MAPK3 MAPT MAST1 MAST2 METTL1 MITF MPP1 MTOR MXD1 NFKBIA NR4A1 NR4A2 NR4A3 PARD3B PDCD4 PDPK1 PDZD7 PDZK1 PDZRN3 PDZRN4 PHAX POLDIP3 PPM1G PPP1R3A PPP1R9A PTPN3 RPTOR SHANK3 SHROOM2 SLC9A3R2 SNTA1 SNTB1 SNTG2 SNX27 SRF SRSF5 SYK SYNJ2BP TAMALIN TOB2 TP53 TSC2 TTK UBE2T VCP WHRN YBX1 YWHAB
Entrez ID 5654 6195
HPRD ID 03725 03402
Ensembl ID ENSG00000166033 ENSG00000117676
Uniprot IDs Q92743 Q15418
PDB IDs 2JOA 2YTW 3NUM 3NWU 3NZI 3TJN 3TJO 3TJQ 2WNT 2Z7Q 2Z7R 2Z7S 3RNY 3TEI 4H3P 4NIF 5CSF 5CSI 5CSJ 5CSN 5N7D 5N7F 5N7G 5V61 5V62
Enriched GO Terms of Interacting Partners?
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