HTRA1 and BMP4

  • Number of citations of the paper that reports this interaction (PubMedID 14973287)
  • 90
  • Data Source:
  • HPRD (in vitro)

HTRA1

BMP4

Description HtrA serine peptidase 1 bone morphogenetic protein 4
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Advanced age-related macular degeneration ( 26691988)
  • Age-related macular degeneration ( 20385819 20385826 22694956 23326517 23455636 23536807 20861866 21665990)
  • Age-related macular degeneration (choroidal neovascularisation) ( 22705344)
  • Age-related macular degeneration (CNV vs. GA) ( 22705344)
  • Age-related macular degeneration (extreme sampling) ( 23577725)
  • Age-related macular degeneration (geographic atrophy) ( 22705344)
  • Age-related macular degeneration (wet) ( 17053108)
  • Coronary artery disease ( 29212778)
  • Disease progression in age-related macular degeneration ( 29346644)
  • Disease progression to choroidal neovascularization form in age-related macular degeneration ( 29346644)
  • Disease progression to geographic atrophy form in age-related macular degeneration ( 29346644)
  • Diverticular disease ( 30177863)
  • Exudative age-related macular degeneration ( 25629512)
  • Laterality in neovascular age-related macular degeneration ( 28775256)
  • Lung function (FEV1/FVC) ( 30061609 30804560)
  • Migraine ( 27322543)
  • Neovascular age-related macular degeneration ( 28703135)
  • Stroke ( 29531354)
  • Systolic blood pressure ( 30224653 30578418)
Interacting Genes 21 interacting genes: APOE BMP4 CAST CDYL COL1A1 COL2A1 COL3A1 COX5A CSNK2B FAM107A FCHSD2 GDF5 GOLGA2 IMPDH1 LRP10 MAPT NOS3 PARD6B RPS6KA1 TENT5A XIAP 18 interacting genes: ACVR2A BGN BMP8B BMPER BMPR1A BMPR1B BMPR2 CHRDL1 CHRDL2 GREM2 HTRA1 NOG RGMB SOSTDC1 STAP2 TDGF1 TWSG1 ZFYVE9
Entrez ID 5654 652
HPRD ID 03725 00207
Ensembl ID ENSG00000166033 ENSG00000125378
Uniprot IDs Q92743 P12644 Q53XC5
PDB IDs 2JOA 2YTW 3NUM 3NWU 3NZI 3TJN 3TJO 3TJQ
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
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