EIF4ENIF1 and EIF4E2

Number of citations of the paper that reports this interaction (PubMedID 16189514)
1016

Data Source:
BioGRID (two hybrid, affinity chromatography technology, affinity chromatography technology, two hybrid)
HPRD (two hybrid)

		EIF4ENIF1	EIF4E2
Description		eukaryotic translation initiation factor 4E nuclear import factor 1	eukaryotic translation initiation factor 4E family member 2
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GO Annotations	Cellular Component	P-body Nucleus Cytoplasm Cytosol Membrane PML Body Nuclear Speck Intracellular Membrane-bounded Organelle	Cytosol MRNA Cap Binding Complex Eukaryotic Translation Initiation Factor 4F Complex
	Molecular Function	RNA Binding MRNA Binding Nuclear Export Signal Receptor Activity Protein Binding	RNA Cap Binding RNA 7-methylguanosine Cap Binding RNA Binding Translation Initiation Factor Activity Protein Binding Translation Factor Activity, RNA Binding Ubiquitin Protein Ligase Binding
	Biological Process	Protein Transport Negative Regulation Of Translation Stem Cell Population Maintenance Negative Regulation Of Neuron Differentiation Nuclear Export	In Utero Embryonic Development Translational Initiation Negative Regulation Of Translation
Pathways			ISG15 antiviral mechanism
Drugs
Diseases
GWAS		Age-related hearing impairment ( 24939585)	Height ( 25282103) Non-small cell lung cancer (survival) ( 21079520)
Interacting Genes		21 interacting genes: ATXN1 CDK6 DDX6 DEF6 DTX2 EFHC1 EIF3E EIF4E EIF4E2 FANCL FDPS HNRNPF KRT19 LSM14A MGAT5B NIN OIP5 SMAD3 SPAG5 TTC19 TXLNA	51 interacting genes: ADAMTSL4 AMOTL2 APP ARIH1 CAB39 CARD9 CBY2 CCL24 CDR2 EIF4EBP1 EIF4EBP3 EIF4ENIF1 FBXO25 GIGYF1 HOMEZ KRT13 KRT19 KRT20 KRT31 KRT40 KRTAP10-5 KRTAP10-8 KRTAP10-9 KRTAP4-12 LZTS2 MAGED1 MAPRE3 MDFI MIPOL1 MVK MYOG NECAB2 NOTCH2NLA PDE4DIP PRDM14 REL SAG SP140 SPAG5 SPRY2 TADA2A TCF4 TGFBRAP1 TLE5 TMCC2 TRIM27 TRIM54 UBXN11 USHBP1 USP54 ZBTB9
Entrez ID		56478	9470
HPRD ID		10456	05798
Ensembl ID		ENSG00000184708	ENSG00000135930
Uniprot IDs		A0A024R1K0 Q9NRA8	B8ZZ50 B8ZZL3 B9A023 O60573 Q53RG0 Q59FE1
PDB IDs		5ANR 6F9W	2JGB 2JGC 5NVK 5NVL 5NVM 5NVN 5XLN
Enriched GO Terms of Interacting Partners?
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