EIF4ENIF1 and EIF3E

Number of citations of the paper that reports this interaction (PubMedID 16343815)
9

Data Source:
HPRD (two hybrid)

		EIF4ENIF1	EIF3E
Description		eukaryotic translation initiation factor 4E nuclear import factor 1	eukaryotic translation initiation factor 3 subunit E
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GO Annotations	Cellular Component	P-body Nucleus Cytoplasm Cytosol Membrane PML Body Nuclear Speck Intracellular Membrane-bounded Organelle	Chromatin Nucleus Nucleoplasm Cytoplasm Cytosol Eukaryotic Translation Initiation Factor 3 Complex Membrane Eukaryotic 43S Preinitiation Complex PML Body Eukaryotic 48S Preinitiation Complex Extracellular Exosome Eukaryotic Translation Initiation Factor 3 Complex, EIF3e
	Molecular Function	RNA Binding MRNA Binding Nuclear Export Signal Receptor Activity Protein Binding	RNA Binding Translation Initiation Factor Activity Protein Binding Cadherin Binding Protein N-terminus Binding
	Biological Process	Protein Transport Negative Regulation Of Translation Stem Cell Population Maintenance Negative Regulation Of Neuron Differentiation Nuclear Export	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Formation Of Cytoplasmic Translation Initiation Complex Translational Initiation Regulation Of Translational Initiation Positive Regulation Of Translation Negative Regulation Of Translational Initiation Positive Regulation Of MRNA Binding
Pathways			L13a-mediated translational silencing of Ceruloplasmin expression Translation initiation complex formation Formation of a pool of free 40S subunits Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit
Drugs
Diseases
GWAS		Age-related hearing impairment ( 24939585)	Coffee consumption ( 31046077) Dupuytren's disease ( 28886342 21732829) Heel bone mineral density ( 30598549) Macular thickness ( 30535121) Male-pattern baldness ( 28196072) Ossification of the posterior longitudinal ligament of the spine ( 25064007)
Interacting Genes		21 interacting genes: ATXN1 CDK6 DDX6 DEF6 DTX2 EFHC1 EIF3E EIF4E EIF4E2 FANCL FDPS HNRNPF KRT19 LSM14A MGAT5B NIN OIP5 SMAD3 SPAG5 TTC19 TXLNA	25 interacting genes: ATM C4orf19 COPS6 COPS7A COPS7B COPS8 DDX24 EIF3C EIF3L EIF4ENIF1 EPAS1 GPAA1 GPBP1L1 HAP1 IFIT1 MAPK1IP1L NDRG1 NSF PRRC2A RUNDC3A SHBG SMAD9 TRIM27 TRIM55 TRIM63
Entrez ID		56478	3646
HPRD ID		10456	03734
Ensembl ID		ENSG00000184708	ENSG00000104408
Uniprot IDs		A0A024R1K0 Q9NRA8	P60228
PDB IDs		5ANR 6F9W	3J8B 3J8C 6FEC
Enriched GO Terms of Interacting Partners?
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