PRPSAP1 and PRPS2

Number of citations of the paper that reports this interaction (PubMedID 9366267)
1

Data Source:
HPRD (in vitro, in vivo)

		PRPSAP1	PRPS2
Description		phosphoribosyl pyrophosphate synthetase associated protein 1	phosphoribosyl pyrophosphate synthetase 2
Image			No pdb structure
GO Annotations	Cellular Component	Ribose Phosphate Diphosphokinase Complex Cytoplasm	Ribose Phosphate Diphosphokinase Complex Cytoplasm
	Molecular Function	Magnesium Ion Binding Ribose Phosphate Diphosphokinase Activity Enzyme Inhibitor Activity Protein Binding Identical Protein Binding	Magnesium Ion Binding Ribose Phosphate Diphosphokinase Activity Protein Binding ATP Binding Kinase Activity Identical Protein Binding Protein Homodimerization Activity
	Biological Process	5-phosphoribose 1-diphosphate Biosynthetic Process Nucleobase-containing Compound Metabolic Process Purine Nucleotide Biosynthetic Process Nucleotide Biosynthetic Process Negative Regulation Of Catalytic Activity	5-phosphoribose 1-diphosphate Biosynthetic Process Nucleobase-containing Compound Metabolic Process Purine Nucleotide Biosynthetic Process Nucleoside Metabolic Process Ribonucleoside Monophosphate Biosynthetic Process Nucleotide Biosynthetic Process Phosphorylation
Pathways			5-Phosphoribose 1-diphosphate biosynthesis
Drugs
Diseases
GWAS		High-grade serous ovarian cancer ( 31469419) Urate levels ( 23263486)	Metabolite levels ( 23823483) Systemic lupus erythematosus ( 26606652)
Interacting Genes		5 interacting genes: DDX19B MAPK1 PLEKHF2 PRPS1 PRPS2	3 interacting genes: NOTCH2NLA NTAQ1 PRPSAP1
Entrez ID		5635	5634
HPRD ID		03151	02414
Ensembl ID		ENSG00000161542	ENSG00000101911
Uniprot IDs		B4DP31 Q14558	A0A140VK41 P11908
PDB IDs		2C4K
Enriched GO Terms of Interacting Partners?
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