PRPS2 and PRPSAP1

Number of citations of the paper that reports this interaction (PubMedID 9366267)
1

Data Source:
HPRD (in vitro, in vivo)

		PRPS2	PRPSAP1
Description		phosphoribosyl pyrophosphate synthetase 2	phosphoribosyl pyrophosphate synthetase associated protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Ribose Phosphate Diphosphokinase Complex Cytoplasm	Ribose Phosphate Diphosphokinase Complex Cytoplasm
	Molecular Function	Magnesium Ion Binding Ribose Phosphate Diphosphokinase Activity Protein Binding ATP Binding Kinase Activity Identical Protein Binding Protein Homodimerization Activity	Magnesium Ion Binding Ribose Phosphate Diphosphokinase Activity Enzyme Inhibitor Activity Protein Binding Identical Protein Binding
	Biological Process	5-phosphoribose 1-diphosphate Biosynthetic Process Nucleobase-containing Compound Metabolic Process Purine Nucleotide Biosynthetic Process Nucleoside Metabolic Process Ribonucleoside Monophosphate Biosynthetic Process Nucleotide Biosynthetic Process Phosphorylation	5-phosphoribose 1-diphosphate Biosynthetic Process Nucleobase-containing Compound Metabolic Process Purine Nucleotide Biosynthetic Process Nucleotide Biosynthetic Process Negative Regulation Of Catalytic Activity
Pathways		5-Phosphoribose 1-diphosphate biosynthesis
Drugs
Diseases
GWAS		Metabolite levels ( 23823483) Systemic lupus erythematosus ( 26606652)	High-grade serous ovarian cancer ( 31469419) Urate levels ( 23263486)
Interacting Genes		3 interacting genes: NOTCH2NLA NTAQ1 PRPSAP1	5 interacting genes: DDX19B MAPK1 PLEKHF2 PRPS1 PRPS2
Entrez ID		5634	5635
HPRD ID		02414	03151
Ensembl ID		ENSG00000101911	ENSG00000161542
Uniprot IDs		A0A140VK41 P11908	B4DP31 Q14558
PDB IDs			2C4K
Enriched GO Terms of Interacting Partners?
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