Description |
mitogen-activated protein kinase 3 |
mitogen-activated protein kinase 14 |
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GO Annotations |
Cellular Component |
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Molecular Function |
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Biological Process |
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Pathways |
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Drugs |
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- Dasatinib
- 4-[5-[2-(1-Phenyl-Ethylamino)-Pyrimidin-4-Yl]-1-Methyl-4-(3-Trifluoromethylphenyl)-1h-Imidazol-2-Yl]-Piperidine
- N-[(3z)-5-Tert-Butyl-2-Phenyl-1,2-Dihydro-3h-Pyrazol-3-Ylidene]-N'-(4-Chlorophenyl)Urea
- 1-(2,6-Dichlorophenyl)-5-(2,4-Difluorophenyl)-7-Piperidin-4-Yl-3,4-Dihydroquinolin-2(1h)-One
- Inhibitor of P38 Kinase
- 6((S)-3-Benzylpiperazin-1-Yl)-3-(Naphthalen-2-Yl)-4-(Pyridin-4-Yl)Pyrazine
- 3-(4-Fluorophenyl)-1-Hydroxy-2-(Pyridin-4-Yl)-1h-Pyrrolo[3,2-B]Pyridine
- 1-(5-Tert-Butyl-2-Methyl-2h-Pyrazol-3-Yl)-3-(4-Chloro-Phenyl)-Urea
- 3-(Benzyloxy)Pyridin-2-Amine
- 1-(2,6-Dichlorophenyl)-5-(2,4-Difluorophenyl)-7-Piperazin-1-Yl-3,4-Dihydroquinazolin-2(1h)-One
- 4-[3-Methylsulfanylanilino]-6,7-Dimethoxyquinazoline
- 1-(5-Tert-Butyl-2-P-Tolyl-2h-Pyrazol-3-Yl)-3-[4-(2-Morpholin-4-Yl-Ethoxy)-Naphthalen-1-Yl]-Urea
- 2-Chlorophenol
- 4-(Fluorophenyl)-1-Cyclopropylmethyl-5-(2-Amino-4-Pyrimidinyl)Imidazole
- SB220025
- 4-(2-HYDROXYBENZYLAMINO)-N-(3-(4-FLUOROPHENOXY)PHENYL)PIPERIDINE-1-SULFONAMIDE
- Triazolopyridine
- KC706
- Talmapimod
- VX-702
- 1-[1-(3-aminophenyl)-3-tert-butyl-1H-pyrazol-5-yl]-3-naphthalen-1-ylurea
- N-ethyl-4-{[5-(methoxycarbamoyl)-2-methylphenyl]amino}-5-methylpyrrolo[2,1-f][1,2,4]triazine-6-carboxamide
- N-[2-methyl-5-(methylcarbamoyl)phenyl]-2-{[(1R)-1-methylpropyl]amino}-1,3-thiazole-5-carboxamide
- Neflamapimod
- N-cyclopropyl-4-methyl-3-[1-(2-methylphenyl)phthalazin-6-yl]benzamide
- 4-PHENOXY-N-(PYRIDIN-2-YLMETHYL)BENZAMIDE
- 4-[5-(3-IODO-PHENYL)-2-(4-METHANESULFINYL-PHENYL)-1H-IMIDAZOL-4-YL]-PYRIDINE
- N-cyclopropyl-2',6-dimethyl-4'-(5-methyl-1,3,4-oxadiazol-2-yl)biphenyl-3-carboxamide
- 4-[3-(4-FLUOROPHENYL)-1H-PYRAZOL-4-YL]PYRIDINE
- 4-{4-[(5-hydroxy-2-methylphenyl)amino]quinolin-7-yl}-1,3-thiazole-2-carbaldehyde
- N-(3-cyanophenyl)-2'-methyl-5'-(5-methyl-1,3,4-oxadiazol-2-yl)-4-biphenylcarboxamide
- N-(cyclopropylmethyl)-2'-methyl-5'-(5-methyl-1,3,4-oxadiazol-2-yl)biphenyl-4-carboxamide
- N~3~-cyclopropyl-N~4~'-(cyclopropylmethyl)-6-methylbiphenyl-3,4'-dicarboxamide
- PH-797804
- 2-fluoro-4-[4-(4-fluorophenyl)-1H-pyrazol-3-yl]pyridine
- 2-{4-[5-(4-chlorophenyl)-4-pyrimidin-4-yl-1H-pyrazol-3-yl]piperidin-1-yl}-2-oxoethanol
- N-(3-TERT-BUTYL-1H-PYRAZOL-5-YL)-N'-{4-CHLORO-3-[(PYRIDIN-3-YLOXY)METHYL]PHENYL}UREA
- N-[4-CHLORO-3-(PYRIDIN-3-YLOXYMETHYL)-PHENYL]-3-FLUORO-
- 3-FLUORO-5-MORPHOLIN-4-YL-N-[3-(2-PYRIDIN-4-YLETHYL)-1H-INDOL-5-YL]BENZAMIDE
- 3-fluoro-N-1H-indol-5-yl-5-morpholin-4-ylbenzamide
- 3-(1-NAPHTHYLMETHOXY)PYRIDIN-2-AMINE
- 3-(2-CHLOROPHENYL)-1-(2-{[(1S)-2-HYDROXY-1,2-DIMETHYLPROPYL]AMINO}PYRIMIDIN-4-YL)-1-(4-METHOXYPHENYL)UREA
- 8-(2-CHLOROPHENYLAMINO)-2-(2,6-DIFLUOROPHENYLAMINO)-9-ETHYL-9H-PURINE-1,7-DIIUM
- 2-(2,6-DIFLUOROPHENOXY)-N-(2-FLUOROPHENYL)-9-ISOPROPYL-9H-PURIN-8-AMINE
- N,4-dimethyl-3-[(1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl)amino]benzamide
- N-cyclopropyl-3-{[1-(2,4-difluorophenyl)-7-methyl-6-oxo-6,7-dihydro-1H-pyrazolo[3,4-b]pyridin-4-yl]amino}-4-methylbenzamide
- N-cyclopropyl-4-methyl-3-{2-[(2-morpholin-4-ylethyl)amino]quinazolin-6-yl}benzamide
- 6-[4-(2-fluorophenyl)-1,3-oxazol-5-yl]-N-(1-methylethyl)-1,3-benzothiazol-2-amine
- 2-(ETHOXYMETHYL)-4-(4-FLUOROPHENYL)-3-[2-(2-HYDROXYPHENOXY)PYRIMIDIN-4-YL]ISOXAZOL-5(2H)-ONE
- [5-AMINO-1-(4-FLUOROPHENYL)-1H-PYRAZOL-4-YL][3-(PIPERIDIN-4-YLOXY)PHENYL]METHANONE
- [5-AMINO-1-(4-FLUOROPHENYL)-1H-PYRAZOL-4-YL](3-{[(2R)-2,3-DIHYDROXYPROPYL]OXY}PHENYL)METHANONE
- 4-[5-(4-FLUORO-PHENYL)-2-(4-METHANESULFINYL-PHENYL)-3H-IMIDAZOL-4-YL]-PYRIDINE
- 4-(4-FLUOROPHENYL)-1-CYCLOROPROPYLMETHYL-5-(4-PYRIDYL)-IMIDAZOLE
- 3-FLUORO-5-MORPHOLIN-4-YL-N-[1-(2-PYRIDIN-4-YLETHYL)-1H-INDOL-6-YL]BENZAMIDE
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Diseases |
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GWAS |
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- Foot ulcer in diabetes and neuropathy ( 28672053)
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Interacting Genes |
171 interacting genes:
AKR1C1
AMOT
ARRB1
ATP1A1
BCL2
BCL3
BTBD10
C1QBP
CASP8
CASP9
CAV1
CCDC6
CDC23
CDC25C
CDC45
CEBPB
CPXM1
CREBBP
CREM
CRP
CUEDC2
DAPK1
DCC
DCP1A
DUSP1
DUSP10
DUSP3
DUSP4
DUSP5
DUSP6
DUSP9
ELK1
ELK4
EPOR
ESR1
ETS1
ETV1
FBXW7
FCGR2B
FKBP2
FOS
FOXP2
FRS2
GAB1
GAB2
GATA1
GATA4
GJA1
GMFB
GRK2
GTF2I
HDAC4
HDAC6
HIF1A
HMMR
HNF4A
HSF1
HSF4
HSPB8
HTRA2
ID2
IER3
INSR
IRS1
ITGAV
ITGB3
JUN
JUND
KRT8
KSR2
L3MBTL3
LAMTOR3
LCK
LIPE
LRPAP1
LYN
MAFG
MAGEA11
MAGED1
MAP2K1
MAP2K2
MAP2K3
MAP3K14
MAPK14
MAPK8
MAPKAPK2
MAPT
MBP
METAP2
MKNK1
MYC
MYLK
MYOG
NAB2
NCKIPSD
NGFR
NTRK1
NTRK3
NUP153
NUP58
PAK2
PDE6G
PEA15
PFKM
PLAT
PLCB1
PPARA
PPP1CA
PPP2CA
PRKCD
PRKCE
PRKCZ
PTPN11
PTPN5
PTPN7
PTPRE
PTPRR
PXN
RAB4A
RAF1
RALGDS
RCAN1
RET
RNF114
RPS6KA1
RPS6KA2
RPS6KA3
RPS6KA4
RPS6KB1
RPTOR
RXRA
SCAND1
SCRIB
SMAD2
SNCG
SORBS3
SOS1
SOX2
SP1
SPIB
SREBF1
SREBF2
STAR
STAT3
STAT5A
STMN1
STMN2
STUB1
SULT4A1
SYK
SYN1
SYNE2
TAL1
TAL2
TCF3
TGIF1
TH
TNFSF11
TOP2B
TP53
TRIM54
TSC2
TTYH3
UBE4B
UBTF
USP21
VDR
VPS52
ZC3HC1
ZNF219
ZNF7
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164 interacting genes:
AIMP1
AKT1
ARNT
ATF2
BCL2
BCL2L1
BICD1
BMI1
CCDC14
CCDC97
CCND2
CD4
CDC25A
CDC25B
CDC25C
CDK4
CDK6
CDKN2A
CDT1
CDX2
CENPC
CEP164
COPS5
CREB1
CSNK2A1
CSNK2A2
CSNK2B
DAB1
DDIT3
DUSP1
DUSP10
DUSP16
DUSP2
DUSP22
DUSP4
DUSP7
DUSP9
DYRK1B
EEA1
EEF1A1
EEF2K
EGFR
EIF4EBP1
ELK1
ELK3
EPB42
EPHA2
EPS15
ESR1
ETV1
FGFR4
FKBP8
FLNA
GADD45A
GATA3
GDF15
GMFB
GORASP2
GRB2
HDAC3
HIVEP1
HNF4A
HSF4
HSPB1
HTRA2
ILKAP
INTS6L
IRAK1
JDP2
JUN
JUNB
KAT2A
KAT2B
KMT2C
KRT18
KRT8
LATS2
LIMK1
MAFA
MAP2K1
MAP2K3
MAP2K4
MAP2K6
MAP2K7
MAP3K10
MAP3K7
MAPK1
MAPK3
MAPK8
MAPKAPK2
MAPKAPK3
MAPKAPK5
MAPT
MARS1
MAX
MBP
MEF2A
MEF2C
MEF2D
MIDEAS
MITF
MKNK1
MKNK2
MOB3B
MUC12
MYC
NCOA3
NF2
NFATC1
NFATC4
NFIC
NKTR
NRL
NUP153
PAK6
PHC2
PI4K2B
PLA2G4A
PLG
PML
PPARGC1A
PPP4R3A
PTPN7
RBSN
RELA
RET
ROBO1
RPL22
RPL41
RPS6KA4
RPS6KA5
S100A9
SCN8A
SH2D1A
SHC1
SLC9A1
SMAD3
SMAD7
SMARCD3
SNAPIN
SPAG9
SPTBN1
SQSTM1
SRPK1
SRSF5
STAT1
STAT4
STK11
STK39
SUPT20H
TAB1
TCF20
TFCP2
TLE5
TMEM63B
TP53
TRAF6
TSC1
UGT2B10
ULK1
YY1AP1
ZFP36L1
ZNF142
ZNHIT1
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Entrez ID |
5595 |
1432 |
HPRD ID |
03479 |
02619 |
Ensembl ID |
ENSG00000102882
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ENSG00000112062
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Uniprot IDs |
L7RXH5
P27361
Q9BWJ1
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A0A024RD15
B4E0K5
L7RSM2
Q16539
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PDB IDs |
2ZOQ
4QTB
6GES
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1A9U
1BL6
1BL7
1BMK
1DI9
1IAN
1KV1
1KV2
1M7Q
1OUK
1OUY
1OVE
1OZ1
1R39
1R3C
1W7H
1W82
1W83
1W84
1WBN
1WBO
1WBS
1WBT
1WBV
1WBW
1WFC
1YQJ
1ZYJ
1ZZ2
1ZZL
2BAJ
2BAK
2BAL
2BAQ
2FSL
2FSM
2FSO
2FST
2GFS
2I0H
2LGC
2NPQ
2OKR
2ONL
2QD9
2RG5
2RG6
2Y8O
2YIS
2YIW
2YIX
2ZAZ
2ZB0
2ZB1
3BV2
3BV3
3BX5
3C5U
3CTQ
3D7Z
3D83
3DS6
3DT1
3E92
3E93
3FC1
3FI4
3FKL
3FKN
3FKO
3FL4
3FLN
3FLQ
3FLS
3FLW
3FLY
3FLZ
3FMH
3FMJ
3FMK
3FML
3FMM
3FMN
3FSF
3FSK
3GC7
3GCP
3GCQ
3GCS
3GCU
3GCV
3GFE
3GI3
3HA8
3HEC
3HEG
3HL7
3HLL
3HP2
3HP5
3HRB
3HUB
3HUC
3HV3
3HV4
3HV5
3HV6
3HV7
3HVC
3IPH
3ITZ
3IW5
3IW6
3IW7
3IW8
3K3I
3K3J
3KF7
3KQ7
3L8S
3L8X
3LFA
3LFB
3LFC
3LFD
3LFE
3LFF
3LHJ
3MGY
3MH0
3MH1
3MH2
3MH3
3MPA
3MPT
3MVL
3MVM
3MW1
3NEW
3NNU
3NNV
3NNW
3NNX
3NWW
3O8P
3O8T
3O8U
3OBG
3OBJ
3OC1
3OCG
3OD6
3ODY
3ODZ
3OEF
3PG3
3QUD
3QUE
3RIN
3ROC
3S3I
3S4Q
3U8W
3UVP
3UVQ
3UVR
3ZS5
3ZSG
3ZSH
3ZSI
3ZYA
4A9Y
4AA0
4AA4
4AA5
4AAC
4DLI
4DLJ
4E5A
4E5B
4E6A
4E6C
4E8A
4EH2
4EH3
4EH4
4EH5
4EH6
4EH7
4EH8
4EH9
4EHV
4EWQ
4F9W
4F9Y
4FA2
4GEO
4KIN
4KIP
4KIQ
4L8M
4R3C
4ZTH
5ETA
5ETC
5ETF
5ETI
5ML5
5MTX
5MTY
5MZ3
5N63
5N64
5N65
5N66
5N67
5N68
5O8U
5O8V
5OMG
5OMH
5TBE
5TCO
5WJJ
5XYX
5XYY
6ANL
6HWT
6HWU
6HWV
6M95
6M9L
6OHD
6SFI
6SFJ
6SFK
6SFO
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Enriched GO Terms of Interacting Partners? |
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Tagcloud (Difference) ? |
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Tagcloud (Intersection) ? |
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