USE1 and BSCL2

Number of citations of the paper that reports this interaction (PubMedID 16189514)
1016

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		USE1	BSCL2
Description		unconventional SNARE in the ER 1	BSCL2 lipid droplet biogenesis associated, seipin
Image		No pdb structure
GO Annotations	Cellular Component	Lysosome Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Plasma Membrane Integral Component Of Membrane COPI-coated Vesicle SNARE Complex	Integral Component Of Endoplasmic Reticulum Membrane
	Molecular Function	Protein Binding	Molecular_function Protein Binding
	Biological Process	ER To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To ER Lysosomal Transport Protein Transport Protein Catabolic Process Secretion By Cell	Lipid Catabolic Process Lipid Storage Lipid Droplet Organization Fat Cell Differentiation Negative Regulation Of Lipid Catabolic Process Positive Regulation Of Cold-induced Thermogenesis
Pathways		COPI-dependent Golgi-to-ER retrograde traffic
Drugs
Diseases			Hereditary spastic paraplegia (SPG) Congenital generalized lipodystrophy (CGL) Distal hereditary motor neuropathies (dHMN)
GWAS		Night sleep phenotypes ( 27126917)	Response to anti-retroviral therapy (ddI/d4T) in HIV-1 infection (Grade 3 peripheral neuropathy) ( 24554482) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		6 interacting genes: APP BSCL2 CREB3 LMNA MEOX2 TRIM27	8 interacting genes: CPEB2 NSG1 PLEKHF2 PLIN1 SMIM3 SMLR1 TMEM19 USE1
Entrez ID		55850	26580
HPRD ID		11299	05858
Ensembl ID		ENSG00000053501	ENSG00000168000
Uniprot IDs		Q9NZ43	A0A024R540 A0A024R549 Q96G97
PDB IDs			6DS5
Enriched GO Terms of Interacting Partners?
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