BSCL2 and CPEB2

Number of citations of the paper that reports this interaction (PubMedID 22157746)
30

Data Source:
BioGRID (two hybrid)

		BSCL2	CPEB2
Description		BSCL2 lipid droplet biogenesis associated, seipin	cytoplasmic polyadenylation element binding protein 2
Image			No pdb structure
GO Annotations	Cellular Component	Integral Component Of Endoplasmic Reticulum Membrane	Nucleus Cytoplasm Neuron Projection Synapse Messenger Ribonucleoprotein Complex
	Molecular Function	Molecular_function Protein Binding	Translation Repressor Activity, MRNA Regulatory Element Binding RNA Binding MRNA 3'-UTR Binding GTPase Inhibitor Activity Translation Factor Activity, RNA Binding MRNA 3'-UTR AU-rich Region Binding Ribosome Binding Ribosomal Large Subunit Binding Ribosomal Small Subunit Binding
	Biological Process	Lipid Catabolic Process Lipid Storage Lipid Droplet Organization Fat Cell Differentiation Negative Regulation Of Lipid Catabolic Process Positive Regulation Of Cold-induced Thermogenesis	Translation Cellular Response To Insulin Stimulus Negative Regulation Of GTPase Activity Cellular Response To Oxidative Stress Cellular Response To Arsenic-containing Substance Cellular Response To Hypoxia Negative Regulation Of Cytoplasmic Translational Elongation Negative Regulation Of Cytoplasmic Translation
Pathways
Drugs
Diseases		Hereditary spastic paraplegia (SPG) Congenital generalized lipodystrophy (CGL) Distal hereditary motor neuropathies (dHMN)
GWAS		Response to anti-retroviral therapy (ddI/d4T) in HIV-1 infection (Grade 3 peripheral neuropathy) ( 24554482) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Cognitive flexibility ( 30134085)
Interacting Genes		8 interacting genes: CPEB2 NSG1 PLEKHF2 PLIN1 SMIM3 SMLR1 TMEM19 USE1	21 interacting genes: ATG2A ATP1B2 BSCL2 C2CD2L CAPN15 COPS7A ERI3 GAA GABBR1 GPX7 KEAP1 MT-ATP6 NECAB2 OTUB1 PIGS PSAP PUF60 SEMA4B SORBS3 SPARC TUBA1A
Entrez ID		26580	132864
HPRD ID		05858	16744
Ensembl ID		ENSG00000168000	ENSG00000137449
Uniprot IDs		A0A024R540 A0A024R549 Q96G97	Q7Z5Q1
PDB IDs		6DS5
Enriched GO Terms of Interacting Partners?
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