BSCL2 and PLIN1

Number of citations of the paper that reports this interaction (PubMedID 30940487)
1

Data Source:
BioGRID (affinity chromatography technology, protein complementation assay)

		BSCL2	PLIN1
Description		BSCL2 lipid droplet biogenesis associated, seipin	perilipin 1
Image			No pdb structure
GO Annotations	Cellular Component	Integral Component Of Endoplasmic Reticulum Membrane	Endoplasmic Reticulum Lipid Droplet Cytosol
	Molecular Function	Molecular_function Protein Binding	Lipid Binding
	Biological Process	Lipid Catabolic Process Lipid Storage Lipid Droplet Organization Fat Cell Differentiation Negative Regulation Of Lipid Catabolic Process Positive Regulation Of Cold-induced Thermogenesis	Lipid Metabolic Process Lipid Catabolic Process
Pathways			Triglyceride catabolism Transcriptional regulation of white adipocyte differentiation NR1H2 & NR1H3 regulate gene expression linked to triglyceride lipolysis in adipose
Drugs
Diseases		Hereditary spastic paraplegia (SPG) Congenital generalized lipodystrophy (CGL) Distal hereditary motor neuropathies (dHMN)
GWAS		Response to anti-retroviral therapy (ddI/d4T) in HIV-1 infection (Grade 3 peripheral neuropathy) ( 24554482) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	HDL cholesterol ( 30275531)
Interacting Genes		8 interacting genes: CPEB2 NSG1 PLEKHF2 PLIN1 SMIM3 SMLR1 TMEM19 USE1	4 interacting genes: ABHD5 BSCL2 LIPE PRKACA
Entrez ID		26580	5346
HPRD ID		05858	01364
Ensembl ID		ENSG00000168000	ENSG00000166819
Uniprot IDs		A0A024R540 A0A024R549 Q96G97	O60240
PDB IDs		6DS5
Enriched GO Terms of Interacting Partners?
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