EXOC1 and ATG14

Number of citations of the paper that reports this interaction (PubMedID 21241894)
123

Data Source:
BioGRID (two hybrid, affinity chromatography technology)

		EXOC1	ATG14
Description		exocyst complex component 1	autophagy related 14
Image		No pdb structure
GO Annotations	Cellular Component	Exocyst Cytoplasm Cytosol Plasma Membrane Membrane Perinuclear Region Of Cytoplasm Flemming Body Cytoplasmic Side Of Apical Plasma Membrane	Autophagosome Membrane Autophagosome Endoplasmic Reticulum Membrane Cytosol Axoneme Phagophore Assembly Site Membrane Phosphatidylinositol 3-kinase Complex, Class III Mitochondria-associated ER Membrane Phagocytic Vesicle Extrinsic Component Of Omegasome Membrane Extrinsic Component Of Phagophore Assembly Site Membrane
	Molecular Function	Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding GTP-Rho Binding	Protein Binding GTPase Binding
	Biological Process	Exocytosis Golgi To Plasma Membrane Transport Protein Transport Viral Process Regulation Of Macroautophagy Phosphatidylinositol-mediated Signaling Positive Regulation Of Protein Secretion Exocyst Localization Defense Response To Virus	Autophagosome Assembly Mitophagy Regulation Of Protein Phosphorylation Negative Regulation Of Protein Phosphorylation Positive Regulation Of Protein Phosphorylation Endosome To Lysosome Transport Cellular Response To Starvation Posttranscriptional Regulation Of Gene Expression Macroautophagy Autophagosome Membrane Docking Cellular Response To Glucose Starvation Positive Regulation Of Phosphatidylinositol 3-kinase Activity Regulation Of Protein Complex Stability Regulation Of Triglyceride Metabolic Process Response To Mitochondrial Depolarisation
Pathways		Translocation of SLC2A4 (GLUT4) to the plasma membrane Insulin processing VxPx cargo-targeting to cilium	Macroautophagy
Drugs
Diseases
GWAS		Cerebrospinal P-tau181p levels ( 28247064) Cervical cancer ( 23817570) Daytime sleep phenotypes ( 27126917) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Blood protein levels ( 28240269) Platelet distribution width ( 27863252) Statin-induced myopathy ( 31220337) Testicular germ cell tumor ( 28604728)
Interacting Genes		27 interacting genes: ATG14 CCDC88A CCDC93 CCSER2 CDC5L CEP295 COLEC12 DISC1 DST KANSL1 KDM1A LUC7L2 MACF1 MTNR1A NUF2 RALA RB1CC1 RESF1 RUBCN SFR1 SH3BP5 SPTAN1 SRGAP2 SYBU TRAF3IP1 TRIM9 TRIO	6 interacting genes: ATG13 EXOC1 RACK1 SNAPIN STX17 ULK2
Entrez ID		55763	22863
HPRD ID		07615	13820
Ensembl ID		ENSG00000090989	ENSG00000126775
Uniprot IDs		A0A024RDA1 A1LT29 Q9NV70	Q6ZNE5
PDB IDs			6HOL
Enriched GO Terms of Interacting Partners?
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