ATG14 and ATG13

Number of citations of the paper that reports this interaction (PubMedID 27046250)
56

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, pull down)

		ATG14	ATG13
Description		autophagy related 14	autophagy related 13
Image
GO Annotations	Cellular Component	Autophagosome Membrane Autophagosome Endoplasmic Reticulum Membrane Cytosol Axoneme Phagophore Assembly Site Membrane Phosphatidylinositol 3-kinase Complex, Class III Mitochondria-associated ER Membrane Phagocytic Vesicle Extrinsic Component Of Omegasome Membrane Extrinsic Component Of Phagophore Assembly Site Membrane	Phagophore Assembly Site Mitochondrion Endoplasmic Reticulum Membrane Cytosol Extrinsic Component Of Membrane Atg1/ULK1 Kinase Complex
	Molecular Function	Protein Binding GTPase Binding	Protein Binding Protein Kinase Regulator Activity Protein Kinase Binding
	Biological Process	Autophagosome Assembly Mitophagy Regulation Of Protein Phosphorylation Negative Regulation Of Protein Phosphorylation Positive Regulation Of Protein Phosphorylation Endosome To Lysosome Transport Cellular Response To Starvation Posttranscriptional Regulation Of Gene Expression Macroautophagy Autophagosome Membrane Docking Cellular Response To Glucose Starvation Positive Regulation Of Phosphatidylinositol 3-kinase Activity Regulation Of Protein Complex Stability Regulation Of Triglyceride Metabolic Process Response To Mitochondrial Depolarisation	Autophagosome Assembly Autophagy Of Mitochondrion Mitophagy Macroautophagy Regulation Of Macroautophagy Activation Of Protein Kinase Activity Protein Localization To Phagophore Assembly Site Piecemeal Microautophagy Of The Nucleus Autophagy Of Nucleus Response To Mitochondrial Depolarisation Positive Regulation Of Protein Targeting To Mitochondrion
Pathways		Macroautophagy	Macroautophagy
Drugs
Diseases
GWAS		Blood protein levels ( 28240269) Platelet distribution width ( 27863252) Statin-induced myopathy ( 31220337) Testicular germ cell tumor ( 28604728)	Age at first sexual intercourse ( 27089180) Alzheimer's disease or fasting glucose levels (pleiotropy) ( 30805717) Autism spectrum disorder or schizophrenia ( 28540026) Headache ( 29397368) Immunoglobulin A ( 20694011) Reaction time ( 29844566) Schizophrenia ( 29483656) Selective IgA deficiency ( 27723758)
Interacting Genes		6 interacting genes: ATG13 EXOC1 RACK1 SNAPIN STX17 ULK2	12 interacting genes: APP ATG101 ATG14 GABARAP GABARAPL1 GABARAPL2 MAP1LC3A MAP1LC3B MAP1LC3C RB1CC1 SMCR8 ULK1
Entrez ID		22863	9776
HPRD ID		13820	13809
Ensembl ID		ENSG00000126775	ENSG00000175224
Uniprot IDs		Q6ZNE5	A8K0S6 O75143
PDB IDs		6HOL	3WAN 3WAO 3WAP 5C50 5XUY 5XV1 5XV3 5XV4 5XV6 6HYN
Enriched GO Terms of Interacting Partners?
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