ARFGAP1 and MAP1LC3B

Number of citations of the paper that reports this interaction (PubMedID 21900206)
114

Data Source:
BioGRID (two hybrid)

		ARFGAP1	MAP1LC3B
Description		ADP ribosylation factor GTPase activating protein 1	microtubule associated protein 1 light chain 3 beta
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GO Annotations	Cellular Component	Golgi Membrane Cytosol Postsynaptic Density Synapse	Autophagosome Membrane Intracellular Mitochondrion Autophagosome Cytosol Microtubule Axoneme Endomembrane System Organelle Membrane Cytoplasmic Vesicle Intracellular Membrane-bounded Organelle
	Molecular Function	GTPase Activator Activity Protein Binding Metal Ion Binding	Protein Binding Microtubule Binding Ubiquitin Protein Ligase Binding
	Biological Process	ER To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To ER Protein Transport Regulation Of Endocytosis Regulation Of ARF Protein Signal Transduction IRE1-mediated Unfolded Protein Response Positive Regulation Of GTPase Activity	Autophagosome Assembly Autophagy Of Mitochondrion Autophagy Cellular Response To Nitrogen Starvation Cellular Response To Starvation Macroautophagy Autophagosome Maturation
Pathways		XBP1(S) activates chaperone genes COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic Clathrin-mediated endocytosis	Macroautophagy Pink/Parkin Mediated Mitophagy TBC/RABGAPs Receptor Mediated Mitophagy Pexophagy
Drugs
Diseases
GWAS			General factor of neuroticism ( 30867560) Major depressive disorder ( 22472876) Metabolite levels ( 23823483) Neuroticism ( 29255261)
Interacting Genes		34 interacting genes: APOB APOC3 APOE APP ARF1 ASB10 COPA COPS5 CSNK1D CYTH2 FOS GABARAPL2 GGCX GRN HRAS KDELR1 KRTAP10-9 KRTAP3-2 KRTAP9-2 LRRK2 MAP1LC3B MED27 PRKACB RAB23 RABGAP1L RASIP1 REEP5 RFC3 RGS2 RPL11 SMN1 TK1 TMED2 TRIM23	65 interacting genes: AAMP ADD1 ADNP AMBRA1 ANK2 ARFGAP1 ATG13 ATG3 ATG4A ATG4B ATG4C ATG4D ATG7 BNIP3 BRD3 CASP8 CCSER2 CLTA CUL3 DBI DBN1 DNMT3B EED EPS8 EVA1A FLCN FUNDC1 FYCO1 GABARAPL2 GORASP2 KBTBD7 KLHL5 KXD1 LUC7L2 MKRN1 MRFAP1 MYBL2 NBR1 NEDD4 RAD1 RAP1GAP RB1CC1 RETREG2 RIPOR1 RPLP1 SAFB SEM1 SMARCB1 SNU13 SPAG9 SQSTM1 TAF7 TAX1BP1 TBC1D17 TBC1D25 TBC1D9 TBC1D9B TBK1 THAP7 TMOD3 TNIP1 TRIM21 ULK1 UPF2 VHL
Entrez ID		55738	81631
HPRD ID		06443	14358
Ensembl ID		ENSG00000101199	ENSG00000140941
Uniprot IDs		Q53F62 Q8N6T3	Q658J6 Q9GZQ8
PDB IDs		3DWD 3O47	1V49 2LUE 2N9X 2ZJD 3VTU 3VTV 3VTW 3WAO 3X0W 4WAA 5D94 5DCN 5GMV 5MS2 5MS5 5MS6 5V4K 5W9A 5XAC 5XAD 5XAE 6J04
Enriched GO Terms of Interacting Partners?
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