MAP1LC3B and ATG3

Number of citations of the paper that reports this interaction (PubMedID 16303767)
60

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vitro)

		MAP1LC3B	ATG3
Description		microtubule associated protein 1 light chain 3 beta	autophagy related 3
Image
GO Annotations	Cellular Component	Autophagosome Membrane Intracellular Mitochondrion Autophagosome Cytosol Microtubule Axoneme Endomembrane System Organelle Membrane Cytoplasmic Vesicle Intracellular Membrane-bounded Organelle	Cytoplasmic Ubiquitin Ligase Complex Cytosol
	Molecular Function	Protein Binding Microtubule Binding Ubiquitin Protein Ligase Binding	Protein Binding Atg8 Ligase Activity Atg12 Transferase Activity Ubiquitin-like Protein Transferase Activity Enzyme Binding
	Biological Process	Autophagosome Assembly Autophagy Of Mitochondrion Autophagy Cellular Response To Nitrogen Starvation Cellular Response To Starvation Macroautophagy Autophagosome Maturation	Autophagosome Assembly Autophagy Of Mitochondrion Cellular Protein Modification Process Protein Targeting To Membrane Macroautophagy Protein Ubiquitination Mitochondrial Fragmentation Involved In Apoptotic Process Autophagy Of Nucleus Negative Regulation Of Phagocytosis Regulation Of Cilium Assembly
Pathways		Macroautophagy Pink/Parkin Mediated Mitophagy TBC/RABGAPs Receptor Mediated Mitophagy Pexophagy	Macroautophagy
Drugs
Diseases
GWAS		General factor of neuroticism ( 30867560) Major depressive disorder ( 22472876) Metabolite levels ( 23823483) Neuroticism ( 29255261)	Asthma (childhood onset) ( 23829686)
Interacting Genes		65 interacting genes: AAMP ADD1 ADNP AMBRA1 ANK2 ARFGAP1 ATG13 ATG3 ATG4A ATG4B ATG4C ATG4D ATG7 BNIP3 BRD3 CASP8 CCSER2 CLTA CUL3 DBI DBN1 DNMT3B EED EPS8 EVA1A FLCN FUNDC1 FYCO1 GABARAPL2 GORASP2 KBTBD7 KLHL5 KXD1 LUC7L2 MKRN1 MRFAP1 MYBL2 NBR1 NEDD4 RAD1 RAP1GAP RB1CC1 RETREG2 RIPOR1 RPLP1 SAFB SEM1 SMARCB1 SNU13 SPAG9 SQSTM1 TAF7 TAX1BP1 TBC1D17 TBC1D25 TBC1D9 TBC1D9B TBK1 THAP7 TMOD3 TNIP1 TRIM21 ULK1 UPF2 VHL	6 interacting genes: ATG12 ATG7 BECN1 GABARAP GABARAPL2 MAP1LC3B
Entrez ID		81631	64422
HPRD ID		14358	10654
Ensembl ID		ENSG00000140941	ENSG00000144848
Uniprot IDs		Q658J6 Q9GZQ8	Q9NT62
PDB IDs		1V49 2LUE 2N9X 2ZJD 3VTU 3VTV 3VTW 3WAO 3X0W 4WAA 5D94 5DCN 5GMV 5MS2 5MS5 5MS6 5V4K 5W9A 5XAC 5XAD 5XAE 6J04	4NAW
Enriched GO Terms of Interacting Partners?
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