ATF7IP and PLEKHB2

Number of citations of the paper that reports this interaction (PubMedID 15231748)
85

Data Source:
HPRD (two hybrid)

		ATF7IP	PLEKHB2
Description		activating transcription factor 7 interacting protein	pleckstrin homology domain containing B2
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Transcription Factor Complex Cytosol Nuclear Body	Integral Component Of Membrane Recycling Endosome Membrane
	Molecular Function	Transcription Corepressor Activity Protein Binding ATPase Activity	Protein Binding Phosphatidylinositol-3,4,5-trisphosphate Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II DNA Methylation Viral Process Regulation Of Protein Stability Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Regulation Of RNA Polymerase II Transcriptional Preinitiation Complex Assembly Protein Stabilization Positive Regulation Of Methylation-dependent Chromatin Silencing	Regulation Of Cell Differentiation
Pathways		PKMTs methylate histone lysines
Drugs
Diseases
GWAS		Breast cancer ( 24143190) Cognitive ability (MTAG) ( 29186694) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Height ( 31562340) Household income (MTAG) ( 31844048) Intelligence (MTAG) ( 29326435) Prostate-specific antigen levels ( 23359319) Testicular germ cell cancer ( 20543847) Testicular germ cell tumor ( 28604728 28604732 23666240)
Interacting Genes		69 interacting genes: A2M ACTB ACTG1 AP1B1 CADM1 CEP250 COL4A2 CREB1 CREBBP CSPG4 DISC1 DMTF1 DNM2 EPG5 FLNB FLT4 GMEB1 GTF2E2 GTF2F1 GTF2H1 HEYL HLA-B HSPG2 KIF13A KRT7 LAMA4 LAMA5 LAMC1 LUC7L2 MACF1 MBD1 MCAM MED4 MRI1 NOMO1 NPR1 PAPPA PAPPA2 PCDH1 PEX6 PIAS3 PKD1 PLEKHB2 POLR2C POLR2D POLR2G PRSS8 PSG3 QRICH1 RPS3A RRBP1 SENP3 SETDB1 SLC12A4 SMAD4 SP1 SPTBN1 SREBF2 STBD1 STRN SUMO2 SUSD1 SVEP1 TRIP12 TTC3 UBE2I ZBTB6 ZNF350 ZNF518A	9 interacting genes: ATF7IP BHLHE40 C1orf94 CDA DAZAP2 EPN1 MAP3K1 STAM2 UPF1
Entrez ID		55729	55041
HPRD ID		09811	15144
Ensembl ID		ENSG00000171681	ENSG00000115762
Uniprot IDs		A0A024RAY1 B3KNI7 B3KQF8 Q6VMQ6	A0A024QZ35 A0A0A0MSE9 A0A0A0MSI4 B4DJB7 Q96CS7
PDB IDs		2RPQ	3AJ4 3VIA
Enriched GO Terms of Interacting Partners?
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