GPATCH2L and PRDM14

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		GPATCH2L	PRDM14
Description		G-patch domain containing 2 like	PR/SET domain 14
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Nucleus Nucleoplasm
	Molecular Function	Protein Binding	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity RNA Binding Protein Binding Methyltransferase Activity Chromatin DNA Binding Sequence-specific DNA Binding Metal Ion Binding
	Biological Process		Negative Regulation Of Transcription By RNA Polymerase II Cell Morphogenesis Cell Fate Specification Inner Cell Mass Cell Fate Commitment Germ Cell Development Embryo Implantation Fertilization Germ-line Stem Cell Population Maintenance Histone H3-R26 Methylation Somatic Stem Cell Population Maintenance Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Regulation Of DNA Methylation Homeostasis Of Number Of Cells Within A Tissue Inactivation Of Paternal X Chromosome Positive Regulation Of Flagellated Sperm Motility Positive Regulation Of Stem Cell Population Maintenance
Pathways			Transcriptional regulation of pluripotent stem cells
Drugs
Diseases
GWAS			Schizophrenia ( 30285260) Testicular germ cell tumor ( 28604728 28604732 23666240)
Interacting Genes		25 interacting genes: APP CCDC33 CEP70 DIP2A KDM1A KRT40 KRTAP10-9 KRTAP4-12 LZTS2 MDFI MEOX2 PRDM14 PRMT1 PRMT8 RBPMS SUV39H1 THAP1 TRIM41 ZBTB48 ZBTB8A ZNF165 ZNF263 ZNF398 ZNF408 ZNF473	32 interacting genes: AKAP9 ATPAF2 BAG4 BCAR3 BEX2 CASP8 CDCA7L CHEK2 DGCR6 EED EIF4E2 ERBB2 EZH2 GPATCH2L HEXIM2 HSPB7 ID3 IDH1 MIA3 NDUFB9 PALB2 PAX2 PLEKHF2 PRKAB2 PSMA1 PTPRJ RAD51D RBM10 RCOR3 SUZ12 TEKT4 TTC32
Entrez ID		55668	63978
HPRD ID		16594	11457
Ensembl ID		ENSG00000089916	ENSG00000147596
Uniprot IDs		A0A024R6E4 A0A024R6J0 Q9NWQ4	Q9GZV8
PDB IDs
Enriched GO Terms of Interacting Partners?
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