PRKAB2 and KCTD5

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		PRKAB2	KCTD5
Description		protein kinase AMP-activated non-catalytic subunit beta 2	potassium channel tetramerization domain containing 5
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Nucleotide-activated Protein Kinase Complex	Nucleus Cytoplasm Cytosol Cul3-RING Ubiquitin Ligase Complex
	Molecular Function	AMP-activated Protein Kinase Activity Protein Binding Protein Kinase Binding Identical Protein Binding	Protein Binding Identical Protein Binding Protein-containing Complex Binding Cullin Family Protein Binding
	Biological Process	Protein Phosphorylation Fatty Acid Biosynthetic Process Carnitine Shuttle Cell Cycle Arrest Signal Transduction Macroautophagy Regulation Of Macroautophagy Regulation Of Fatty Acid Biosynthetic Process Regulation Of Catalytic Activity Positive Regulation Of Cold-induced Thermogenesis Regulation Of Signal Transduction By P53 Class Mediator	Viral Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Protein Homooligomerization
Pathways		Translocation of SLC2A4 (GLUT4) to the plasma membrane Macroautophagy AMPK inhibits chREBP transcriptional activation activity AMPK inhibits chREBP transcriptional activation activity Carnitine metabolism Activation of PPARGC1A (PGC-1alpha) by phosphorylation Energy dependent regulation of mTOR by LKB1-AMPK TP53 Regulates Metabolic Genes Regulation of TP53 Activity through Phosphorylation Lipophagy Activation of AMPK downstream of NMDARs
Drugs		Adenosine monophosphate Acetylsalicylic acid
Diseases
GWAS
Interacting Genes		74 interacting genes: ADAMTSL4 BANP BEND5 BLZF1 CALCOCO2 CASP6 CCDC33 CDX4 CREB3L1 CRX CSNK2B DAO DDIT4L DICER1 DST EPM2A FDX1 FLNC GATA1 GATAD2B GET4 GOLGA2 GRN IHO1 IKZF1 IKZF3 KCTD5 KLF15 KRT40 KRTAP1-3 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP4-12 KRTAP4-2 KRTAP5-9 KRTAP9-2 KRTAP9-4 LZTS2 MAGED1 MDFI MEOX2 NEBL PIAS2 PNMA1 PRDM14 PRKAA1 PRKAG1 PRKAG2 PSME3 PYGM RACK1 RBPMS REL RHEBL1 RIMBP3 SPRY2 SSX2IP STX11 STX19 TADA2A TASOR2 TCF4 TLE5 TP53 TP53BP2 TRAF1 TRAF2 TRIM10 UBXN11 YY1AP1 ZBTB32	8 interacting genes: CD1A CUL3 EP300 GIT2 GORASP2 NEK6 NXF1 PRKAB2
Entrez ID		5565	54442
HPRD ID		04117	13768
Ensembl ID		ENSG00000131791	ENSG00000167977
Uniprot IDs		O43741	Q9NXV2
PDB IDs		2F15 2V8Q 2V92 2V9J 2Y8L 2Y8Q 2YA3 4CFH 4EAI 4EAJ 4RER 4REW 6B2E	3DRX 3DRY 3DRZ
Enriched GO Terms of Interacting Partners?
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