PPP1R9A and PRKAR1B

Number of citations of the paper that reports this interaction (PubMedID 12052877)
39

Data Source:
HPRD (in vivo, in vitro)

		PPP1R9A	PRKAR1B
Description		protein phosphatase 1 regulatory subunit 9A	protein kinase cAMP-dependent type I regulatory subunit beta
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GO Annotations	Cellular Component	Cytoplasm Cytosol Postsynaptic Density Actin Cytoskeleton Cell Junction Filopodium Dendrite Cortical Actin Cytoskeleton Neuromuscular Junction Neuronal Cell Body Dendritic Spine Neck Postsynaptic Actin Cytoskeleton Glutamatergic Synapse Growth Cone Lamellipodium	Cytosol Plasma Membrane CAMP-dependent Protein Kinase Complex Ciliary Base Schaffer Collateral - CA1 Synapse Hippocampal Mossy Fiber To CA3 Synapse Glutamatergic Synapse
	Molecular Function	Protein Binding Protein C-terminus Binding Protein Phosphatase 1 Binding Protein Kinase Binding Protein Domain Specific Binding Identical Protein Binding Ion Channel Binding Actin Filament Binding GTPase Binding	CAMP-dependent Protein Kinase Inhibitor Activity Protein Binding CAMP-dependent Protein Kinase Regulator Activity CAMP Binding Protein Kinase A Catalytic Subunit Binding 3',5'-cyclic-GMP Phosphodiesterase Activity
	Biological Process	Actin Filament Organization Aging Calcium-mediated Signaling Regulation Of Actin Filament Polymerization Neuron Projection Development Positive Regulation Of Protein Kinase Activity Regulation Of Filopodium Assembly Negative Regulation Of Stress Fiber Assembly Regulation Of Synapse Structural Plasticity Regulation Of Synapse Assembly Excitatory Postsynaptic Potential Positive Regulation Of Dendritic Spine Development Regulation Of Dendritic Spine Morphogenesis Cellular Response To Toxic Substance Postsynaptic Actin Cytoskeleton Organization Negative Regulation Of Long-term Synaptic Potentiation Positive Regulation Of Long-term Synaptic Depression Negative Regulation Of Spontaneous Neurotransmitter Secretion	Renal Water Homeostasis Protein Phosphorylation Blood Coagulation Learning Or Memory CGMP-mediated Signaling Activation Of Protein Kinase A Activity Modulation Of Chemical Synaptic Transmission Cellular Response To Glucagon Stimulus Regulation Of Synaptic Vesicle Cycle Negative Regulation Of CAMP-dependent Protein Kinase Activity
Pathways			PKA activation PKA activation in glucagon signalling DARPP-32 events Glucagon-like Peptide-1 (GLP1) regulates insulin secretion Vasopressin regulates renal water homeostasis via Aquaporins CREB1 phosphorylation through the activation of Adenylate Cyclase Hedgehog 'off' state ADORA2B mediated anti-inflammatory cytokines production FCGR3A-mediated IL10 synthesis Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS		Glucocorticoid-induced osteonecrosis (age 10 years and older) ( 26265699) Waist circumference ( 28552196)	Hematocrit ( 27863252) Hemoglobin concentration ( 27863252) Plasma free amino acid levels ( 30659259) Red blood cell count ( 27863252)
Interacting Genes		8 interacting genes: ACTG1 PPP1CA PPP1R2 PPP1R9B PRKAR1B RPS6KA1 RPS6KB1 TGOLN2	8 interacting genes: AKAP1 EGFR PPP1R9A PRKAR1A SMAD3 SMAD4 WNK1 WRN
Entrez ID		55607	5575
HPRD ID		16000	01485
Ensembl ID		ENSG00000158528	ENSG00000188191
Uniprot IDs		A4D1I0 B7ZLX4 Q9ULJ8	P31321
PDB IDs		1WF8	4DIN 4F9K
Enriched GO Terms of Interacting Partners?
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