PRCC and SRSF2

Number of citations of the paper that reports this interaction (PubMedID 11313942)
13

Data Source:
HPRD (in vivo)

		PRCC	SRSF2
Description		proline rich mitotic checkpoint control factor	serine and arginine rich splicing factor 2
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nuclear Speck	Nucleus Nucleoplasm Spliceosomal Complex Cytoplasm Cytosol PML Body Nuclear Speck Interchromatin Granule
	Molecular Function	Protein Binding	Transcription Corepressor Activity RNA Binding Protein Kinase C Binding Protein Binding Pre-mRNA Binding
	Biological Process	MRNA Splicing, Via Spliceosome Mitotic Cell Cycle Checkpoint	Mitotic Cell Cycle Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome MRNA Processing RNA Export From Nucleus MRNA Export From Nucleus RNA Splicing MRNA 3'-end Processing Response To Vitamin E MRNA Cis Splicing, Via Spliceosome Negative Regulation Of Nucleic Acid-templated Transcription
Pathways		mRNA Splicing - Major Pathway	Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination
Drugs
Diseases		Renal cell carcinoma
GWAS		SjÃ¶gren's syndrome ( 28076899)
Interacting Genes		10 interacting genes: CSNK2A1 EGFR HOMER3 LSM2 MAD2L2 PPIL2 PRPF19 RBM10 SRSF2 TOE1	34 interacting genes: ADAP1 BARD1 CCNL1 CCNL2 CDK12 CDK6 CEP72 CIR1 CSNK2A1 FUS GEMIN2 GOLGA2 KAT5 KRT31 KRT40 LIG4 LZTS2 NCF1 PRCC SCAF11 SNRNP70 SREK1 SRPK2 SRSF11 SRSF3 SRSF4 TCF4 TRA2B TRIM27 U2AF1 UBQLN4 YTHDC1 ZRANB2 ZRSR2
Entrez ID		5546	6427
HPRD ID		01562	02888
Ensembl ID		ENSG00000143294	ENSG00000161547
Uniprot IDs		A0A0S2Z456 A0A0S2Z470 Q92733 Q96FT4	A0A024R8U5 Q01130 Q53FN0
PDB IDs			2KN4 2LEA 2LEB 2LEC
Enriched GO Terms of Interacting Partners?
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