SHFL and FBXL12

		SHFL	FBXL12
Description		shiftless antiviral inhibitor of ribosomal frameshifting	F-box and leucine rich repeat protein 12
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	P-body Nucleus Nucleoplasm Cytoplasm Cytosol Viral Replication Complex	Nucleus Cytosol SCF Ubiquitin Ligase Complex
	Molecular Function	RNA Binding Protein Binding Ribosome Binding Sequence-specific MRNA Binding	Protein Binding Ubiquitin Protein Ligase Activity
	Biological Process	Regulation Of Translational Termination Response To Type I Interferon Response To Interferon-gamma Response To Type III Interferon Response To Interferon-beta Negative Regulation Of Viral Genome Replication Defense Response To Virus Viral Translational Frameshifting Negative Regulation Of Translational Frameshifting	G2/M Transition Of Mitotic Cell Cycle Protein Polyubiquitination SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Post-translational Protein Modification Regulation Of Cell Cycle
Pathways			Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS			Pursuit maintenance gain ( 29064472)
Interacting Genes		34 interacting genes: ADAMTSL4 CADPS CCDC136 DRICH1 DTNBP1 ECSIT FBXL12 IKZF1 KRT40 KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP2-4 KRTAP4-12 KRTAP4-2 KRTAP5-9 KRTAP9-2 LZTS2 MAGEA1 MDFI MEOX2 MID2 MTUS2 NOTCH2NLA PDE4DIP SPRY2 SSX2IP TCF4 TERF1 TNS2 TRAF1	22 interacting genes: A2M ALDH3A1 APOE CDC37 CDKN1C DOCK8 ECSIT FXYD3 LNX1 MARCHF2 MAST1 PSEN1 PSEN2 PSME3 RNF32 SHFL SMAD1 TGFBR1 UBE2D3 ZNF44 ZNF562 ZNF823
Entrez ID		55337	54850
HPRD ID		07747	12363
Ensembl ID		ENSG00000130813	ENSG00000127452
Uniprot IDs		Q9NUL5	Q9NXK8
PDB IDs
Enriched GO Terms of Interacting Partners?
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