PPP3CC and THAP7

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		PPP3CC	THAP7
Description		protein phosphatase 3 catalytic subunit gamma	THAP domain containing 7
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Cytosol Calcineurin Complex Glutamatergic Synapse Presynaptic Cytosol	Nuclear Chromatin Nucleoplasm Nuclear Speck Nuclear Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding Calmodulin Binding Calmodulin-dependent Protein Phosphatase Activity Metal Ion Binding	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Identical Protein Binding Metal Ion Binding Protein N-terminus Binding C2H2 Zinc Finger Domain Binding
	Biological Process	Protein Dephosphorylation Brain Development Calcineurin-NFAT Signaling Cascade Calcineurin-mediated Signaling Positive Regulation Of Synaptic Vesicle Endocytosis Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway	Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Transcription, DNA-templated
Pathways		Activation of BAD and translocation to mitochondria DARPP-32 events
Drugs
Diseases
GWAS		General risk tolerance (MTAG) ( 30643258) HIV-1 viral setpoint ( 20205591) Verbal declarative memory ( 25648963)
Interacting Genes		11 interacting genes: AMPH APP BCL2 BMPR1B CABIN1 CSNK2B HAX1 ITPKC SDC2 TGFBR1 THAP7	35 interacting genes: APP CCDC85B CCNDBP1 EHMT2 FBXO7 GNAI1 GOLGA2 H3C1 H4C1 HCFC1 HDAC3 KRT31 KRT40 KRTAP10-3 KRTAP10-8 KRTAP4-12 LNX1 LURAP1 LZTS2 MAP1LC3B MDFI MID2 MTUS2 NOTCH2NLA PELI2 PHC2 PIN1 PPP3CC SET TAF1B TFIP11 THAP11 TRAF1 TRAF2 ZDHHC17
Entrez ID		5533	80764
HPRD ID		00236	15500
Ensembl ID		ENSG00000120910	ENSG00000184436
Uniprot IDs		P48454	Q9BT49
PDB IDs
Enriched GO Terms of Interacting Partners?
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