PEF1 and FOXR2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		PEF1	FOXR2
Description		penta-EF-hand domain containing 1	forkhead box R2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Endoplasmic Reticulum COPII Vesicle Coat Cul3-RING Ubiquitin Ligase Complex Extracellular Exosome	Nuclear Chromatin Nucleoplasm
	Molecular Function	RNA Binding Calcium Ion Binding Protein Binding Protein Heterodimerization Activity Protein Dimerization Activity Calcium-dependent Protein Binding Protein Binding, Bridging Involved In Substrate Recognition For Ubiquitination	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Sequence-specific DNA Binding
	Biological Process	ER To Golgi Vesicle-mediated Transport Neural Crest Formation Neural Crest Cell Development Protein Ubiquitination COPII Vesicle Coating Response To Calcium Ion Positive Regulation Of Protein Monoubiquitination	Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs		Calcium Citrate Calcium Phosphate
Diseases
GWAS		Body mass index ( 26426971) Cognitive ability ( 29186694) Cognitive ability (MTAG) ( 29186694) General cognitive ability ( 29844566) Intelligence (MTAG) ( 29326435) Severe aortic features in Marfan syndrome ( 30087447)	Mean corpuscular volume ( 29403010)
Interacting Genes		14 interacting genes: ALG2 CALCOCO2 CEP55 CUL3 DAZAP2 DMRTB1 EWSR1 FOXR2 HGS KLHL12 NR0B2 PDCD6 SEC31A TFG	2 interacting genes: PEF1 SUV39H1
Entrez ID		553115	139628
HPRD ID		10143	13552
Ensembl ID		ENSG00000162517	ENSG00000189299
Uniprot IDs		A0A384MQX5 Q9UBV8	Q6PJQ5
PDB IDs
Enriched GO Terms of Interacting Partners?
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