FOXR2 and PEF1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		FOXR2	PEF1
Description		forkhead box R2	penta-EF-hand domain containing 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleoplasm	Golgi Membrane Cytoplasm Endoplasmic Reticulum COPII Vesicle Coat Cul3-RING Ubiquitin Ligase Complex Extracellular Exosome
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Sequence-specific DNA Binding	RNA Binding Calcium Ion Binding Protein Binding Protein Heterodimerization Activity Protein Dimerization Activity Calcium-dependent Protein Binding Protein Binding, Bridging Involved In Substrate Recognition For Ubiquitination
	Biological Process	Regulation Of Transcription By RNA Polymerase II	ER To Golgi Vesicle-mediated Transport Neural Crest Formation Neural Crest Cell Development Protein Ubiquitination COPII Vesicle Coating Response To Calcium Ion Positive Regulation Of Protein Monoubiquitination
Pathways
Drugs			Calcium Citrate Calcium Phosphate
Diseases
GWAS		Mean corpuscular volume ( 29403010)	Body mass index ( 26426971) Cognitive ability ( 29186694) Cognitive ability (MTAG) ( 29186694) General cognitive ability ( 29844566) Intelligence (MTAG) ( 29326435) Severe aortic features in Marfan syndrome ( 30087447)
Interacting Genes		2 interacting genes: PEF1 SUV39H1	14 interacting genes: ALG2 CALCOCO2 CEP55 CUL3 DAZAP2 DMRTB1 EWSR1 FOXR2 HGS KLHL12 NR0B2 PDCD6 SEC31A TFG
Entrez ID		139628	553115
HPRD ID		13552	10143
Ensembl ID		ENSG00000189299	ENSG00000162517
Uniprot IDs		Q6PJQ5	A0A384MQX5 Q9UBV8
PDB IDs
Enriched GO Terms of Interacting Partners?
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