PEF1 and SEC31A

Number of citations of the paper that reports this interaction (PubMedID 27716508)
29

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, pull down)

		PEF1	SEC31A
Description		penta-EF-hand domain containing 1	SEC31 homolog A, COPII coat complex component
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Endoplasmic Reticulum COPII Vesicle Coat Cul3-RING Ubiquitin Ligase Complex Extracellular Exosome	Golgi Membrane Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol ER To Golgi Transport Vesicle Membrane Vesicle Coat COPII Vesicle Coat COPII-coated ER To Golgi Transport Vesicle Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm Endoplasmic Reticulum Exit Site
	Molecular Function	RNA Binding Calcium Ion Binding Protein Binding Protein Heterodimerization Activity Protein Dimerization Activity Calcium-dependent Protein Binding Protein Binding, Bridging Involved In Substrate Recognition For Ubiquitination	Structural Molecule Activity Protein Binding Calcium-dependent Protein Binding
	Biological Process	ER To Golgi Vesicle-mediated Transport Neural Crest Formation Neural Crest Cell Development Protein Ubiquitination COPII Vesicle Coating Response To Calcium Ion Positive Regulation Of Protein Monoubiquitination	Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Intracellular Protein Transport ER To Golgi Vesicle-mediated Transport Endoplasmic Reticulum Organization Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II IRE1-mediated Unfolded Protein Response COPII Vesicle Coating Response To Calcium Ion Cargo Loading Into COPII-coated Vesicle COPII-coated Vesicle Budding
Pathways			COPII-mediated vesicle transport MHC class II antigen presentation XBP1(S) activates chaperone genes Antigen Presentation: Folding, assembly and peptide loading of class I MHC
Drugs		Calcium Citrate Calcium Phosphate
Diseases
GWAS		Body mass index ( 26426971) Cognitive ability ( 29186694) Cognitive ability (MTAG) ( 29186694) General cognitive ability ( 29844566) Intelligence (MTAG) ( 29326435) Severe aortic features in Marfan syndrome ( 30087447)	Adult asthma ( 27611488) Neutrophil percentage of white cells ( 27863252)
Interacting Genes		14 interacting genes: ALG2 CALCOCO2 CEP55 CUL3 DAZAP2 DMRTB1 EWSR1 FOXR2 HGS KLHL12 NR0B2 PDCD6 SEC31A TFG	12 interacting genes: APC ARIH1 KLHL12 PDCD6 PEF1 PFDN1 PRNP REL SEC13 TNNT1 TSC22D2 USP8
Entrez ID		553115	22872
HPRD ID		10143	15314
Ensembl ID		ENSG00000162517	ENSG00000138674
Uniprot IDs		A0A384MQX5 Q9UBV8	A0A024RDH6 A1LU61 O94979
PDB IDs			3WXA
Enriched GO Terms of Interacting Partners?
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