PSPC1 and SFPQ

Number of citations of the paper that reports this interaction (PubMedID 28514442)
199

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vivo)

		PSPC1	SFPQ
Description		paraspeckle component 1	splicing factor proline and glutamine rich
Image
GO Annotations	Cellular Component	Fibrillar Center Nucleus Nucleoplasm Cytoplasm Nuclear Matrix Nuclear Speck Paraspeckles	Chromatin Nucleus Nucleoplasm Nuclear Matrix Nuclear Speck Dendrite Cytoplasm Paraspeckles RNA Polymerase II Transcription Factor Complex
	Molecular Function	Transcription Regulatory Region Sequence-specific DNA Binding Nucleic Acid Binding RNA Binding Protein Binding E-box Binding	Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding Nucleic Acid Binding DNA Binding Chromatin Binding RNA Binding Protein Binding Protein Homodimerization Activity Histone Deacetylase Binding Transcription Regulatory Region DNA Binding E-box Binding
	Biological Process	MRNA Splicing, Via Spliceosome Activation Of Innate Immune Response Regulation Of Transcription, DNA-templated Regulation Of Circadian Rhythm Innate Immune Response Negative Regulation Of Transcription, DNA-templated Rhythmic Process	Negative Regulation Of Transcription By RNA Polymerase II Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome Double-strand Break Repair Via Homologous Recombination Activation Of Innate Immune Response Regulation Of Transcription, DNA-templated MRNA Processing RNA Splicing Regulation Of Circadian Rhythm Negative Regulation Of Circadian Rhythm Innate Immune Response Positive Regulation Of Sister Chromatid Cohesion Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Rhythmic Process Histone H3 Deacetylation Dendritic Transport Of Messenger Ribonucleoprotein Complex Positive Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway
Pathways			PTK6 Regulates Proteins Involved in RNA Processing Suppression of apoptosis
Drugs			Copper Artenimol
Diseases
GWAS		Waist circumference adjusted for body mass index ( 28552196)	Allergic disease (asthma, hay fever or eczema) ( 29083406) Endometrial cancer ( 21499250) Hip circumference ( 28552196)
Interacting Genes		8 interacting genes: ESR1 KRT31 KRTAP13-1 LRIF1 NONO SFPQ TCERG1 WBP4	29 interacting genes: APBB1 AR CSNK2A1 ERG ESR1 EXOSC5 FHL2 FUS GAS7 H3-4 JPT1 NONO PIN1 PPARG PPP1CA PRPF40A PSPC1 PTBP1 RAC1 SIN3A SMAD5 SNRPA SREK1 TCERG1 TOP1 UBC UBE2I WBP4 ZMYM2
Entrez ID		55269	6421
HPRD ID		10172	07284
Ensembl ID		ENSG00000121390	ENSG00000116560
Uniprot IDs		Q8WXF1	A0A384N5Z8 P23246 Q86VG2
PDB IDs		3SDE 5IFN 5WPA	4WII 4WIJ 4WIK 5WPA 6NCQ
Enriched GO Terms of Interacting Partners?
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