NTAQ1 and PTS

Number of citations of the paper that reports this interaction (PubMedID 19060904)
283

Data Source:
BioGRID (two hybrid)

		NTAQ1	PTS
Description		N-terminal glutamine amidase 1	6-pyruvoyltetrahydropterin synthase
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GO Annotations	Cellular Component	Nucleus Cytosol	Cytoplasm Mitochondrion Cytosol
	Molecular Function	Protein Binding Protein-N-terminal Asparagine Amidohydrolase Activity Protein-N-terminal Glutamine Amidohydrolase Activity	6-pyruvoyltetrahydropterin Synthase Activity Protein Binding Identical Protein Binding Metal Ion Binding
	Biological Process	Cellular Protein Modification Process	Cellular Amino Acid Metabolic Process Tetrahydrobiopterin Biosynthetic Process Central Nervous System Development Cofactor Metabolic Process
Pathways			Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
Drugs			Biopterin
Diseases			Phenylketonuria (PKU); Hyperphenylalaninemia, BH4-deficient
GWAS			Heel bone mineral density ( 30598549) Objective response to lithium treatment ( 26503763)
Interacting Genes		106 interacting genes: ACTB ACTG1 AMOT AMOTL2 APIP ASL BLMH BLOC1S6 C1orf50 CAPN3 CBFA2T2 CBS CBY2 CCDC102B CCDC184 CDA CDR2 CEP55 COG6 COIL CRYAA CTBP1 CTH DAB1 DCTPP1 DHPS DNM2 EDARADD EIF2B1 ETV6 FTH1 GAS7 GMCL1 GMDS GNMT GOLGA2 HPRT1 HSD17B14 IKZF3 JAKMIP2 JUP KASH5 KCNH1 KCTD1 KLHL12 KRT31 KRTAP10-5 KRTAP10-7 KRTAP4-2 KRTAP5-9 KRTAP9-2 KRTAP9-4 LMNA LNX2 LONRF1 LZTFL1 LZTS2 MAGEA11 MARCHF10 MDFI MIF MIOS MTUS2 NAGK NCOA5 NECAB2 NME1 NPL NT5C1A NUDT14 PCBD1 PNMA1 PNMA5 PPCDC PRMT1 PRPS2 PSME3 PTS PYGM RABAC1 RBBP8 RBPMS ROPN1 RPIA SEPTIN3 SFN SIAH1 SMN1 SSX2IP STX11 TCL1A THAP1 TLE5 TMEM239 TNR TOLLIP TRAF1 TRIM27 TRIM54 TRIP13 TSC22D1 VAC14 VCP XIAP ZBTB8A ZNF341	10 interacting genes: COIL DDX10 FNDC5 FXR2 LNX1 NTAQ1 PBRM1 PRKG2 SDCBP THAP10
Entrez ID		55093	5805
HPRD ID		07653	11840
Ensembl ID		ENSG00000156795	ENSG00000150787
Uniprot IDs		A0A3B3ITD7 A0A3B3ITI2 E5RHC2 Q96HA8	Q03393
PDB IDs		3C9Q 4W79	3I2B
Enriched GO Terms of Interacting Partners?
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