PTS and FNDC5

Number of citations of the paper that reports this interaction (PubMedID 11591653)
41

		PTS	FNDC5
Description		6-pyruvoyltetrahydropterin synthase	fibronectin type III domain containing 5
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GO Annotations	Cellular Component	Cytoplasm Mitochondrion Cytosol	Extracellular Region Peroxisomal Membrane Endoplasmic Reticulum Plasma Membrane Integral Component Of Membrane
	Molecular Function	6-pyruvoyltetrahydropterin Synthase Activity Protein Binding Identical Protein Binding Metal Ion Binding	Molecular_function Hormone Activity
	Biological Process	Cellular Amino Acid Metabolic Process Tetrahydrobiopterin Biosynthetic Process Central Nervous System Development Cofactor Metabolic Process	Signal Transduction Biological_process Response To Muscle Activity Positive Regulation Of Brown Fat Cell Differentiation
Pathways		Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
Drugs		Biopterin
Diseases		Phenylketonuria (PKU); Hyperphenylalaninemia, BH4-deficient
GWAS		Heel bone mineral density ( 30598549) Objective response to lithium treatment ( 26503763)
Interacting Genes		10 interacting genes: COIL DDX10 FNDC5 FXR2 LNX1 NTAQ1 PBRM1 PRKG2 SDCBP THAP10	1 interacting genes: PTS
Entrez ID		5805	252995
HPRD ID		11840	17009
Ensembl ID		ENSG00000150787	ENSG00000160097
Uniprot IDs		Q03393	Q8NAU1
PDB IDs		3I2B	4LSD
Enriched GO Terms of Interacting Partners?
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