EPN1 and DAZAP2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		EPN1	DAZAP2
Description		epsin 1	DAZ associated protein 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol Plasma Membrane Clathrin-coated Pit	Cytoplasm Nuclear Speck Protein-containing Complex
	Molecular Function	Protein Binding Lipid Binding	Protein Binding Receptor Tyrosine Kinase Binding Mitogen-activated Protein Kinase Kinase Kinase Binding Identical Protein Binding Protein Serine/threonine Kinase Activator Activity WW Domain Binding
	Biological Process	In Utero Embryonic Development Endocytosis Notch Signaling Pathway Female Pregnancy Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Embryonic Organ Development Membrane Organization Negative Regulation Of Sprouting Angiogenesis	Positive Regulation Of Protein Serine/threonine Kinase Activity
Pathways		EGFR downregulation Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis
Drugs		1,4-Diethylene Dioxide 1D-myo-inositol 1,4,5-trisphosphate
Diseases
GWAS		Major depressive disorder ( 23377640)
Interacting Genes		24 interacting genes: AP2A1 AP2A2 CDK1 CEP126 CLTC CRMP1 DAZAP2 EPS15 EPS15L1 FBXO25 HIP1R LAPTM5 MAP3K1 MED31 PLEKHB2 REPS2 RNF11 SCNN1A SCNN1B SCNN1G SMURF1 TFAP2A UBC ZBTB16	91 interacting genes: AATF ARID5A ATXN1 ATXN1L BAG3 BATF2 C1orf94 CALCOCO2 CCDC120 CDK4 CEP70 CLASRP COL4A2 COL4A5 CXCL12 DAB1 DAZ1 DAZL DCUN1D1 EPN1 EXD3 FAM168A FBN3 GPSM1 HGS HIP1 INCA1 KRTAP19-5 KRTAP8-1 LASP1 LMO2 MAGED1 MED31 NDUFA5 NEDD4 NEDD4L NOC4L NOTCH1 OPTN OTULIN PEF1 PLEKHB2 PLSCR1 POGZ POLI PRR20A RABGEF1 RBFOX1 RBFOX2 RBM11 RBPMS RHOXF2 RNF115 RNF208 ROR2 RPS27A SEPTIN2 SMAP2 SMURF2 SOX6 SQSTM1 STAM2 STAT6 TAX1BP1 TCF7L2 TENT5B TENT5C TEX37 TLE1 TNIP3 TOLLIP UBA52 UBAC1 UBASH3A UBASH3B UBB UBC UBE2D4 UBE2E2 UBE3A UBQLN4 USP5 VHLL VPS37C WDR73 WWP1 ZC3H10 ZFAND2B ZFYVE9 ZNF34 ZNF581
Entrez ID		29924	9802
HPRD ID		06270	08463
Ensembl ID		ENSG00000063245	ENSG00000183283
Uniprot IDs		A0A024R4S1 Q9Y6I3	A0A024R110 Q15038
PDB IDs		1INZ 1KYD
Enriched GO Terms of Interacting Partners?
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