POU2AF1 and SLC22A2

Number of citations of the paper that reports this interaction (PubMedID 11483518)
23

Data Source:
HPRD (two hybrid, in vitro)

		POU2AF1	SLC22A2
Description		POU class 2 homeobox associating factor 1	solute carrier family 22 member 2
Image			No pdb structure
GO Annotations	Cellular Component	RNA Polymerase II Transcription Factor Complex	Plasma Membrane Integral Component Of Plasma Membrane Membrane Extracellular Exosome Presynapse
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding RNA Polymerase II Core Promoter Sequence-specific DNA Binding Transcription Coregulator Activity Transcription Coactivator Activity Protein Binding	Organic Cation Transmembrane Transporter Activity
	Biological Process	Transcription By RNA Polymerase II Humoral Immune Response Positive Regulation Of Transcription By RNA Polymerase II	Drug Transmembrane Transport Neurotransmitter Secretion Body Fluid Secretion Organic Cation Transport Neurotransmitter Biosynthetic Process
Pathways			Neurotransmitter clearance Norepinephrine Neurotransmitter Release Cycle Abacavir transmembrane transport Na+/Cl- dependent neurotransmitter transporters Organic cation transport
Drugs
Diseases
GWAS		Celiac disease ( 22057235) Corneal structure ( 23291589) Diverticular disease ( 30177863) Hodgkin's lymphoma ( 30194254) Low urine pH ( 30476138) Multiple sclerosis ( 31604244) Primary biliary cholangitis ( 23000144 28062665) Serum urea levels ( 30808845) Urine pH measurement ( 30476138)	Body mass index ( 26426971 25673413) Body mass index (age>50) ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971) Chronic kidney disease ( 31152163 20383146) Creatinine levels ( 31015462 29403010 20383145) Estimated glomerular filtration rate ( 31152163 31015462 31451708 30604766) Estimated glomerular filtration rate in diabetes ( 31451708) Estimated glomerular filtration rate in non-diabetics ( 31451708) Familial squamous cell lung carcinoma ( 29924316) Glomerular filtration rate ( 27588450 29403010) Glomerular filtration rate (creatinine) ( 28452372 26831199) Glomerular filtration rate in non diabetics (creatinine) ( 26831199) Kidney stones ( 31729369) Lipoprotein (a) levels ( 26377243) Lipoprotein (a) levels in coronary artery disease (percutaneous coronary intervention) ( 31186284) Prostate cancer ( 26034056) Serum metabolite levels ( 23093944) Waist circumference ( 26785701)
Interacting Genes		19 interacting genes: GATA2 GCC2 GTF2H1 GTF2I MSX2 NAB1 NOTCH1 PAX8 POU2F1 POU2F2 PTPN11 RHOXF2 SIAH1 SIAH2 SLC22A1 SLC22A2 SMAD2 SUB1 SYK	9 interacting genes: AGO3 CST9L ETV5 EXT2 GTF2B HYAL3 LSM4 POU2AF1 SUMO2
Entrez ID		5450	6582
HPRD ID		03126	04008
Ensembl ID		ENSG00000110777	ENSG00000112499
Uniprot IDs		Q16633	O15244
PDB IDs		1CQT
Enriched GO Terms of Interacting Partners?
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