POU2AF1 and SLC22A1

Number of citations of the paper that reports this interaction (PubMedID 11136971)
46

Data Source:
HPRD (in vitro)

		POU2AF1	SLC22A1
Description		POU class 2 homeobox associating factor 1	solute carrier family 22 member 1
Image			No pdb structure
GO Annotations	Cellular Component	RNA Polymerase II Transcription Factor Complex	Plasma Membrane Integral Component Of Plasma Membrane Membrane Basolateral Plasma Membrane
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding RNA Polymerase II Core Promoter Sequence-specific DNA Binding Transcription Coregulator Activity Transcription Coactivator Activity Protein Binding	Acetylcholine Transmembrane Transporter Activity Dopamine:sodium Symporter Activity Norepinephrine:sodium Symporter Activity Protein Binding Secondary Active Organic Cation Transmembrane Transporter Activity Organic Cation Transmembrane Transporter Activity Quaternary Ammonium Group Transmembrane Transporter Activity Identical Protein Binding
	Biological Process	Transcription By RNA Polymerase II Humoral Immune Response Positive Regulation Of Transcription By RNA Polymerase II	Neurotransmitter Transport Drug Transmembrane Transport Establishment Or Maintenance Of Transmembrane Electrochemical Gradient Organic Cation Transport Quaternary Ammonium Group Transport Epinephrine Transport Norepinephrine Uptake Ammonium Transmembrane Transport Dopamine Uptake Acetate Ester Transport
Pathways			Neurotransmitter clearance Norepinephrine Neurotransmitter Release Cycle Abacavir transmembrane transport Na+/Cl- dependent neurotransmitter transporters Organic cation transport
Drugs
Diseases
GWAS		Celiac disease ( 22057235) Corneal structure ( 23291589) Diverticular disease ( 30177863) Hodgkin's lymphoma ( 30194254) Low urine pH ( 30476138) Multiple sclerosis ( 31604244) Primary biliary cholangitis ( 23000144 28062665) Serum urea levels ( 30808845) Urine pH measurement ( 30476138)	Blood metabolite levels ( 24816252) Blood metabolite ratios ( 24816252) Blood protein levels ( 28240269) Body mass index ( 26426971) Body mass index (age>50) ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971) Gout ( 22179738) LDL cholesterol levels x long total sleep time interaction (2df test) ( 31719535) LDL cholesterol levels x short total sleep time interaction (2df test) ( 31719535) Lipoprotein (a) levels ( 26377243) Medication use (HMG CoA reductase inhibitors) ( 31015401) Metabolic traits ( 21886157) Prostate cancer ( 26034056 21743057) Serum metabolite levels ( 23093944) Urinary metabolite levels in chronic kidney disease ( 29545352 31959995)
Interacting Genes		19 interacting genes: GATA2 GCC2 GTF2H1 GTF2I MSX2 NAB1 NOTCH1 PAX8 POU2F1 POU2F2 PTPN11 RHOXF2 SIAH1 SIAH2 SLC22A1 SLC22A2 SMAD2 SUB1 SYK	3 interacting genes: CERS2 OS9 POU2AF1
Entrez ID		5450	6580
HPRD ID		03126	04007
Ensembl ID		ENSG00000110777	ENSG00000175003
Uniprot IDs		Q16633	O15245
PDB IDs		1CQT
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
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