LURAP1 and AMOT

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		LURAP1	AMOT
Description		leucine rich adaptor protein 1	angiomotin
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Actomyosin Intracellular Membrane-bounded Organelle	Ruffle Nucleoplasm Cytosol Actin Filament Plasma Membrane Bicellular Tight Junction COP9 Signalosome External Side Of Plasma Membrane Lamellipodium Cell Junction Endocytic Vesicle Cytoplasmic Vesicle
	Molecular Function	Protein Binding	Protein Binding Signaling Receptor Activity Angiostatin Binding
	Biological Process	Positive Regulation Of Cytokine Production Cell Migration Actomyosin Structure Organization Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling	Angiogenesis Vasculogenesis In Utero Embryonic Development Gastrulation With Mouth Forming Second Establishment Of Cell Polarity Involved In Ameboidal Cell Migration Chemotaxis Negative Regulation Of Angiogenesis Actin Cytoskeleton Organization Regulation Of Cell Migration Negative Regulation Of GTPase Activity Cellular Protein Localization Hippo Signaling Positive Regulation Of Embryonic Development Cell Migration Involved In Gastrulation Blood Vessel Endothelial Cell Migration Regulation Of Small GTPase Mediated Signal Transduction
Pathways
Drugs
Diseases
GWAS		Body mass index ( 26426971)
Interacting Genes		17 interacting genes: AMOT BLOC1S6 CCDC112 CCDC185 CSNK1D DOCK10 HAUS1 HGS PRPF31 SNAP29 TCEANC THAP7 TPM3 TXLNB U2AF2 ZNF417 ZNF821	21 interacting genes: ACTA1 APP C1orf216 KRT15 KRT31 LATS2 LMO4 LURAP1 MAGEA4 MAGI1 MAPK3 MED4 NEDD4 NEDD4L NTAQ1 PIN1 PLG PTPA SEPTIN1 SNAPC5 UNC119
Entrez ID		541468	154796
HPRD ID		18478	02327
Ensembl ID		ENSG00000171357	ENSG00000126016
Uniprot IDs		Q96LR2	Q4VCS5
PDB IDs			6JJX
Enriched GO Terms of Interacting Partners?
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