AMOT and PTPA

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		AMOT	PTPA
Description		angiomotin	protein phosphatase 2 phosphatase activator
Image
GO Annotations	Cellular Component	Ruffle Nucleoplasm Cytosol Actin Filament Plasma Membrane Bicellular Tight Junction COP9 Signalosome External Side Of Plasma Membrane Lamellipodium Cell Junction Endocytic Vesicle Cytoplasmic Vesicle	Protein Phosphatase Type 2A Complex Nucleus Nucleoplasm Cytoplasm Calcium Channel Complex Extracellular Exosome
	Molecular Function	Protein Binding Signaling Receptor Activity Angiostatin Binding	Peptidyl-prolyl Cis-trans Isomerase Activity Signaling Receptor Binding Protein Binding ATP Binding Protein Tyrosine Phosphatase Activator Activity ATPase Activity Protein Phosphatase Regulator Activity Protein Homodimerization Activity Protein Phosphatase 2A Binding
	Biological Process	Angiogenesis Vasculogenesis In Utero Embryonic Development Gastrulation With Mouth Forming Second Establishment Of Cell Polarity Involved In Ameboidal Cell Migration Chemotaxis Negative Regulation Of Angiogenesis Actin Cytoskeleton Organization Regulation Of Cell Migration Negative Regulation Of GTPase Activity Cellular Protein Localization Hippo Signaling Positive Regulation Of Embryonic Development Cell Migration Involved In Gastrulation Blood Vessel Endothelial Cell Migration Regulation Of Small GTPase Mediated Signal Transduction	Protein Peptidyl-prolyl Isomerization Mitotic Spindle Organization Negative Regulation Of Phosphoprotein Phosphatase Activity Positive Regulation Of Phosphoprotein Phosphatase Activity Positive Regulation Of Protein Dephosphorylation Negative Regulation Of Protein Dephosphorylation Positive Regulation Of Apoptotic Process Regulation Of Phosphoprotein Phosphatase Activity
Pathways
Drugs
Diseases
GWAS
Interacting Genes		21 interacting genes: ACTA1 APP C1orf216 KRT15 KRT31 LATS2 LMO4 LURAP1 MAGEA4 MAGI1 MAPK3 MED4 NEDD4 NEDD4L NTAQ1 PIN1 PLG PTPA SEPTIN1 SNAPC5 UNC119	24 interacting genes: AKT1 AMOT APP AURKB CCNE1 CCNG1 CCNG2 CSNK2A1 CYLD DTD1 EIF4EBP1 F3 FOXO3 GRIN3A H2AX HDAC4 KISS1R MAPT MID1 PPP2R3A PRKCB RACGAP1 SRC SULT4A1
Entrez ID		154796	5524
HPRD ID		02327	02858
Ensembl ID		ENSG00000126016	ENSG00000119383
Uniprot IDs		Q4VCS5	B4DZF8 F6WIT2 Q15257
PDB IDs		6JJX	2G62 2HV6 2HV7 2IXM 4LAC 4NY3
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?