AMOT and C1orf216

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		AMOT	C1orf216
Description		angiomotin	chromosome 1 open reading frame 216
Image			No pdb structure
GO Annotations	Cellular Component	Ruffle Nucleoplasm Cytosol Actin Filament Plasma Membrane Bicellular Tight Junction COP9 Signalosome External Side Of Plasma Membrane Lamellipodium Cell Junction Endocytic Vesicle Cytoplasmic Vesicle
	Molecular Function	Protein Binding Signaling Receptor Activity Angiostatin Binding	Protein Binding
	Biological Process	Angiogenesis Vasculogenesis In Utero Embryonic Development Gastrulation With Mouth Forming Second Establishment Of Cell Polarity Involved In Ameboidal Cell Migration Chemotaxis Negative Regulation Of Angiogenesis Actin Cytoskeleton Organization Regulation Of Cell Migration Negative Regulation Of GTPase Activity Cellular Protein Localization Hippo Signaling Positive Regulation Of Embryonic Development Cell Migration Involved In Gastrulation Blood Vessel Endothelial Cell Migration Regulation Of Small GTPase Mediated Signal Transduction
Pathways
Drugs
Diseases
GWAS
Interacting Genes		21 interacting genes: ACTA1 APP C1orf216 KRT15 KRT31 LATS2 LMO4 LURAP1 MAGEA4 MAGI1 MAPK3 MED4 NEDD4 NEDD4L NTAQ1 PIN1 PLG PTPA SEPTIN1 SNAPC5 UNC119	28 interacting genes: AMOT CCDC114 CCDC136 CCDC158 CCDC197 CDR2 CEP170P1 GGA1 KRT13 KRT15 KRT31 KRT38 KRT40 MED4 MTUS2 MYRIP NMI NRBF2 NUP62 PSMC6 RALBP1 TLE5 TPM1 TPM3 TRAF1 TRIM54 USHBP1 ZDHHC17
Entrez ID		154796	127703
HPRD ID		02327	08798
Ensembl ID		ENSG00000126016	ENSG00000142686
Uniprot IDs		Q4VCS5	Q8TAB5
PDB IDs		6JJX
Enriched GO Terms of Interacting Partners?
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