PLN and BCL2L13

Number of citations of the paper that reports this interaction (PubMedID 25910212)
127

Data Source:
BioGRID (two hybrid)

		PLN	BCL2L13
Description		phospholamban	BCL2 like 13
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GO Annotations	Cellular Component	Cell Mitochondrion Endoplasmic Reticulum Membrane Mitochondrial Membrane Vesicle Sarcoplasmic Reticulum Membrane Perinuclear Region Of Cytoplasm Calcium Ion-transporting ATPase Complex	Nucleus Mitochondrion Integral Component Of Membrane Mitochondrial Membrane
	Molecular Function	Enzyme Inhibitor Activity Calcium Channel Regulator Activity Protein Binding ATPase Inhibitor Activity Identical Protein Binding Protein Homodimerization Activity ATPase Binding	Protein Binding Cysteine-type Endopeptidase Activator Activity Involved In Apoptotic Process
	Biological Process	Regulation Of The Force Of Heart Contraction Calcium Ion Transport Notch Signaling Pathway Blood Circulation Regulation Of Heart Contraction Response To Zinc Ion Negative Regulation Of Heart Rate Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Negative Regulation Of ATPase Activity Response To Insulin Response To Testosterone Negative Regulation Of Catalytic Activity Cardiac Muscle Tissue Development Regulation Of Cytosolic Calcium Ion Concentration Regulation Of Calcium Ion Transport Negative Regulation Of Calcium Ion Transport Relaxation Of Cardiac Muscle Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Regulation Of Cardiac Muscle Cell Contraction Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway Involved In Heart Process Regulation Of Cardiac Muscle Cell Membrane Potential Regulation Of The Force Of Heart Contraction By Cardiac Conduction Negative Regulation Of Calcium Ion Import Negative Regulation Of Calcium Ion Transmembrane Transporter Activity Negative Regulation Of Calcium Ion Binding Regulation Of Calcium-transporting ATPase Activity Negative Regulation Of Calcium-transporting ATPase Activity Regulation Of Relaxation Of Cardiac Muscle Negative Regulation Of Calcium Ion Import Into Sarcoplasmic Reticulum	Apoptotic Process Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Pathways		Ion homeostasis Ion transport by P-type ATPases
Drugs
Diseases
GWAS		Atrial fibrillation ( 28416818 30061737) Cardiac structure and function ( 19584346) QRS complex (Sokolow-Lyon) ( 27659466) QRS duration ( 27577874 27659466) QT interval ( 23166209 24952745 19305408 19305409 19587794) Resting heart rate ( 27798624)	Baseline cortisol levels in response to low dose short synacthen test in corticosteroid treated asthma ( 29551627) Granulocyte count ( 27863252) Interleukin-10 levels ( 22205395) Myeloid white cell count ( 27863252) Neutrophil count ( 27863252) Sum neutrophil eosinophil counts ( 27863252)
Interacting Genes		14 interacting genes: ATP2A1 ATP2A2 BCL2L13 CREB3 CREB3L1 DMPK DVL3 EDA LDLRAD1 PPP1R3A PRKACA S100A1 SLN TMEM79	15 interacting genes: APP BET1 GABARAPL2 IL17RA MTNR1B NINJ2 PLLP PLN PLP1 TMEM128 TMEM86B TMUB2 UPK1B VAMP3 VAMP4
Entrez ID		5350	23786
HPRD ID		01395	09822
Ensembl ID		ENSG00000198523	ENSG00000099968
Uniprot IDs		P26678 Q5R352	A0A087WTL4 A0A087WW80 A0A087WX97 A0A0A0MR90 A8K5Y4 B2RB43 B7Z238 B7Z737 E9PDD6 F6VJB4 Q86T62 Q9BXK5
PDB IDs		1K9N 1KCH 1PLN 1PLP 1PSL 1ZLL 2HYN	2IPD
Enriched GO Terms of Interacting Partners?
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