ATP6V1B1 and STX1A

Number of citations of the paper that reports this interaction (PubMedID 12651853)
5

Data Source:
BioGRID (pull down)

		ATP6V1B1	STX1A
Description		ATPase H+ transporting V1 subunit B1	syntaxin 1A
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cell Cytoplasm Cytosol Microvillus Basolateral Plasma Membrane Apical Plasma Membrane Lateral Plasma Membrane Vacuolar Proton-transporting V-type ATPase Complex Proton-transporting V-type ATPase, V1 Domain Extracellular Exosome Extrinsic Component Of Synaptic Vesicle Membrane	Extracellular Region Cytosol Plasma Membrane Synaptic Vesicle Voltage-gated Potassium Channel Complex Endomembrane System Postsynaptic Density Integral Component Of Membrane Cell Junction Secretory Granule Integral Component Of Synaptic Vesicle Membrane Axon SNARE Complex Nuclear Membrane Actomyosin Presynaptic Membrane Neuron Projection Presynaptic Active Zone Membrane Synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I Complex Synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II Complex Synaptobrevin 2-SNAP-25-syntaxin-1a Complex Glutamatergic Synapse Integral Component Of Presynaptic Membrane
	Molecular Function	ATP Binding Proton Transmembrane Transporter Activity Hydrolase Activity Protein-containing Complex Binding	SNARE Binding SNAP Receptor Activity Protein Binding Calcium Channel Inhibitor Activity Chloride Channel Inhibitor Activity Kinase Binding Protein Domain Specific Binding Myosin Head/neck Binding Identical Protein Binding ATP-dependent Protein Binding Ion Channel Binding Protein-containing Complex Binding Protein N-terminus Binding Calcium-dependent Protein Binding
	Biological Process	Ossification Renal Water Homeostasis Renal Sodium Ion Transport Prostaglandin Metabolic Process Regulation Of PH Excretion Sensory Perception Of Sound Insulin Receptor Signaling Pathway Regulation Of Gene Expression Regulation Of Macroautophagy Adult Behavior Transferrin Transport Ion Transmembrane Transport Renal Sodium Excretion Olfactory Behavior Inner Ear Morphogenesis PH Reduction ATP Metabolic Process Chloride Ion Homeostasis Calcium Ion Homeostasis Potassium Ion Homeostasis Phagosome Acidification Proton Transmembrane Transport	Positive Regulation Of Neurotransmitter Secretion Intracellular Protein Transport Exocytosis Vesicle Fusion Neurotransmitter Secretion Response To Gravity Positive Regulation Of Norepinephrine Secretion Regulation Of Synaptic Vesicle Priming Glutamate Secretion Synaptic Vesicle Exocytosis Synaptic Vesicle Docking Protein Sumoylation Calcium Ion Regulated Exocytosis Cytokine-mediated Signaling Pathway Insulin Secretion Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Secretion By Cell Positive Regulation Of Catecholamine Secretion SNARE Complex Assembly Positive Regulation Of Calcium Ion-dependent Exocytosis Vesicle Docking Synaptic Vesicle Endocytosis Regulation Of Insulin Secretion Protein Localization To Membrane Positive Regulation Of Excitatory Postsynaptic Potential
Pathways		ROS and RNS production in phagocytes Insulin receptor recycling Transferrin endocytosis and recycling Amino acids regulate mTORC1 Ion channel transport	Serotonin Neurotransmitter Release Cycle Norepinephrine Neurotransmitter Release Cycle Glutamate Neurotransmitter Release Cycle Dopamine Neurotransmitter Release Cycle Acetylcholine Neurotransmitter Release Cycle Insulin processing Regulation of insulin secretion Other interleukin signaling Toxicity of botulinum toxin type C (BoNT/C) LGI-ADAM interactions Neurexins and neuroligins GABA synthesis, release, reuptake and degradation Insertion of tail-anchored proteins into the endoplasmic reticulum membrane Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
Drugs
Diseases		Distal renal tubular acidosis (RTA type 1)
GWAS		Acne (severe) ( 24927181) Urate levels ( 31578528)
Interacting Genes		5 interacting genes: ACTN4 KDM1A SLC9A3R1 STX1A SUV39H1	60 interacting genes: ABCC9 APBA1 ATP4B ATP6V1B1 CACNA1D CCSER2 CDK5 CFTR CPLX1 CSNK2A1 CSNK2A2 DAPK1 KCNB1 NAPA NAPB NSF PSMA3 RAB27A RIMS1 SCNN1A SCNN1B SCNN1G SDCBP SEC22B SEPTIN2 SEPTIN5 SLC6A1 SLC6A2 SLC6A3 SLC6A4 SLC6A5 SLC6A9 SNAP23 SNAP25 SNAP29 SNPH STX8 STXBP1 STXBP2 STXBP5 STXBP6 SUMO1P1 SYT1 SYT4 SYT7 SYTL4 TRDMT1 TXLNA TXLNB UNC13B VAMP1 VAMP2 VAMP5 VAMP7 VAMP8 VAPB VIM VPS11 VPS16 VPS18
Entrez ID		525	6804
HPRD ID		01887	01721
Ensembl ID		ENSG00000116039	ENSG00000106089
Uniprot IDs		P15313	Q16623 Q75ME0
PDB IDs
Enriched GO Terms of Interacting Partners?
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