STX1A and VPS16

Number of citations of the paper that reports this interaction (PubMedID 17027648)
1

Data Source:
BioGRID (pull down)

		STX1A	VPS16
Description		syntaxin 1A	VPS16 core subunit of CORVET and HOPS complexes
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cytosol Plasma Membrane Synaptic Vesicle Voltage-gated Potassium Channel Complex Endomembrane System Postsynaptic Density Integral Component Of Membrane Cell Junction Secretory Granule Integral Component Of Synaptic Vesicle Membrane Axon SNARE Complex Nuclear Membrane Actomyosin Presynaptic Membrane Neuron Projection Presynaptic Active Zone Membrane Synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I Complex Synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II Complex Synaptobrevin 2-SNAP-25-syntaxin-1a Complex Glutamatergic Synapse Integral Component Of Presynaptic Membrane	Lysosome Lysosomal Membrane Endosome Early Endosome Late Endosome Autophagosome Clathrin-coated Vesicle Axon HOPS Complex Late Endosome Membrane Neuronal Cell Body Recycling Endosome
	Molecular Function	SNARE Binding SNAP Receptor Activity Protein Binding Calcium Channel Inhibitor Activity Chloride Channel Inhibitor Activity Kinase Binding Protein Domain Specific Binding Myosin Head/neck Binding Identical Protein Binding ATP-dependent Protein Binding Ion Channel Binding Protein-containing Complex Binding Protein N-terminus Binding Calcium-dependent Protein Binding	Actin Binding Protein Binding Actin Filament Binding
	Biological Process	Positive Regulation Of Neurotransmitter Secretion Intracellular Protein Transport Exocytosis Vesicle Fusion Neurotransmitter Secretion Response To Gravity Positive Regulation Of Norepinephrine Secretion Regulation Of Synaptic Vesicle Priming Glutamate Secretion Synaptic Vesicle Exocytosis Synaptic Vesicle Docking Protein Sumoylation Calcium Ion Regulated Exocytosis Cytokine-mediated Signaling Pathway Insulin Secretion Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Secretion By Cell Positive Regulation Of Catecholamine Secretion SNARE Complex Assembly Positive Regulation Of Calcium Ion-dependent Exocytosis Vesicle Docking Synaptic Vesicle Endocytosis Regulation Of Insulin Secretion Protein Localization To Membrane Positive Regulation Of Excitatory Postsynaptic Potential	Intracellular Protein Transport Vacuole Organization Endosome To Lysosome Transport Endosomal Transport Regulation Of Vacuole Fusion, Non-autophagic Regulation Of SNARE Complex Assembly Autophagosome Maturation
Pathways		Serotonin Neurotransmitter Release Cycle Norepinephrine Neurotransmitter Release Cycle Glutamate Neurotransmitter Release Cycle Dopamine Neurotransmitter Release Cycle Acetylcholine Neurotransmitter Release Cycle Insulin processing Regulation of insulin secretion Other interleukin signaling Toxicity of botulinum toxin type C (BoNT/C) LGI-ADAM interactions Neurexins and neuroligins GABA synthesis, release, reuptake and degradation Insertion of tail-anchored proteins into the endoplasmic reticulum membrane Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
Drugs
Diseases
GWAS			Metabolite levels ( 23823483)
Interacting Genes		60 interacting genes: ABCC9 APBA1 ATP4B ATP6V1B1 CACNA1D CCSER2 CDK5 CFTR CPLX1 CSNK2A1 CSNK2A2 DAPK1 KCNB1 NAPA NAPB NSF PSMA3 RAB27A RIMS1 SCNN1A SCNN1B SCNN1G SDCBP SEC22B SEPTIN2 SEPTIN5 SLC6A1 SLC6A2 SLC6A3 SLC6A4 SLC6A5 SLC6A9 SNAP23 SNAP25 SNAP29 SNPH STX8 STXBP1 STXBP2 STXBP5 STXBP6 SUMO1P1 SYT1 SYT4 SYT7 SYTL4 TRDMT1 TXLNA TXLNB UNC13B VAMP1 VAMP2 VAMP5 VAMP7 VAMP8 VAPB VIM VPS11 VPS16 VPS18	14 interacting genes: AKTIP FBXO7 HOOK1 HOOK2 HOOK3 MON1B RAB7A RILP STX1A STX7 UVRAG VPS11 VPS18 VPS33A
Entrez ID		6804	64601
HPRD ID		01721	12259
Ensembl ID		ENSG00000106089	ENSG00000215305
Uniprot IDs		Q16623 Q75ME0	Q9H269
PDB IDs			4BX9
Enriched GO Terms of Interacting Partners?
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