PER1 and TNS2

Number of citations of the paper that reports this interaction (PubMedID 25814554)
22

Data Source:
BioGRID (two hybrid)

		PER1	TNS2
Description		period circadian regulator 1	tensin 2
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol	Cell Plasma Membrane Focal Adhesion
	Molecular Function	Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding Transcription Corepressor Binding Protein Binding Transcription Factor Binding Kinase Binding Chromatin DNA Binding Ubiquitin Protein Ligase Binding E-box Binding	Protein Tyrosine Phosphatase Activity Protein Binding Kinase Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Sodium Ion Transport Circadian Rhythm Response To Light Stimulus Entrainment Of Circadian Clock Posttranscriptional Regulation Of Gene Expression Circadian Regulation Of Gene Expression Regulation Of Hair Cycle Regulation Of Circadian Rhythm Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling Entrainment Of Circadian Clock By Photoperiod Histone H3 Acetylation Histone H4 Acetylation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of JNK Cascade Response To CAMP Histone H3 Deacetylation Circadian Regulation Of Translation Regulation Of Cytokine Production Involved In Inflammatory Response Regulation Of P38MAPK Cascade Negative Regulation Of Glucocorticoid Receptor Signaling Pathway	Kidney Development Negative Regulation Of Cell Proliferation Response To Muscle Activity Cellular Homeostasis Collagen Metabolic Process Multicellular Organism Growth Peptidyl-tyrosine Dephosphorylation Intracellular Signal Transduction Negative Regulation Of Insulin Receptor Signaling Pathway Multicellular Organismal Homeostasis
Pathways		Circadian Clock
Drugs
Diseases
GWAS
Interacting Genes		16 interacting genes: CCDC57 CRY1 CRY2 CSNK1D CSNK1E CSNK1G2 CSNK2B DELEC1 GPRASP1 HIF1A PER2 PER3 RBPMS RIPOR2 TIMELESS TNS2	86 interacting genes: ADCK5 AMMECR1 AP1S2 ASB3 AXL BRCA1 C11orf87 COX6B2 CSNK1E DCAF11 DCAF8 DDIT4L DLC1 DOK3 EPB41L4A EPS8L2 ERBB2 ERBB3 FABP7 FAM114A1 FGF21 FGFR1 FOXO1 GATA1 GBA3 GFI1B HUWE1 ID2 IHO1 ITGB3 ITGB5 ITGB7 KIF1A KPRP KRTAP1-3 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP12-2 KRTAP13-1 KRTAP23-1 KRTAP3-1 MPEG1 MT2A MTDH MYBPHL MYH7B NMU NT5C NUBP2 OBSL1 OTX1 PER1 PKP1 PLB1 PLK3 POLR3F RBPMS REEP6 REL RFT1 RNF6 SDCCAG8 SH2B3 SHFL SPATA12 SPRY2 SPRY4 SUV39H1 TBC1D16 TCP10L TEKT5 TENT5A TLE5 TM4SF19 TSC1 TWSG1 WDFY3 ZNF250 ZNF417 ZNF586 ZNF587 ZNF655 ZNF688 ZNRD1
Entrez ID		5187	23371
HPRD ID		03774	16256
Ensembl ID		ENSG00000179094	ENSG00000111077
Uniprot IDs		O15534	A0A024RB48 Q63HR2
PDB IDs		1UL6	2DKQ 2KNO 2L6K 2LOZ 3HQC
Enriched GO Terms of Interacting Partners?
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