PER1 and PER3

Number of citations of the paper that reports this interaction (PubMedID 10837028)
63

Data Source:
HPRD (in vitro)

		PER1	PER3
Description		period circadian regulator 1	period circadian regulator 3
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol	Nucleus Cytoplasm
	Molecular Function	Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding Transcription Corepressor Binding Protein Binding Transcription Factor Binding Kinase Binding Chromatin DNA Binding Ubiquitin Protein Ligase Binding E-box Binding	Transcription Regulatory Region Sequence-specific DNA Binding Transcription Corepressor Binding Protein Binding Transcription Factor Binding Kinase Binding Ubiquitin Protein Ligase Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Sodium Ion Transport Circadian Rhythm Response To Light Stimulus Entrainment Of Circadian Clock Posttranscriptional Regulation Of Gene Expression Circadian Regulation Of Gene Expression Regulation Of Hair Cycle Regulation Of Circadian Rhythm Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling Entrainment Of Circadian Clock By Photoperiod Histone H3 Acetylation Histone H4 Acetylation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of JNK Cascade Response To CAMP Histone H3 Deacetylation Circadian Regulation Of Translation Regulation Of Cytokine Production Involved In Inflammatory Response Regulation Of P38MAPK Cascade Negative Regulation Of Glucocorticoid Receptor Signaling Pathway	Negative Regulation Of Transcription By RNA Polymerase II Response To Light Stimulus Circadian Regulation Of Gene Expression Entrainment Of Circadian Clock By Photoperiod Regulation Of Circadian Sleep/wake Cycle, Sleep Protein Stabilization
Pathways		Circadian Clock
Drugs
Diseases
GWAS			Chronotype ( 30696823) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Morning person ( 30696823) Morning vs. evening chronotype ( 26835600) Ulcerative colitis ( 28067908)
Interacting Genes		16 interacting genes: CCDC57 CRY1 CRY2 CSNK1D CSNK1E CSNK1G2 CSNK2B DELEC1 GPRASP1 HIF1A PER2 PER3 RBPMS RIPOR2 TIMELESS TNS2	9 interacting genes: ARNTL CLOCK CRY1 CRY2 CSNK1D CSNK1E PER1 PER2 SP1
Entrez ID		5187	8863
HPRD ID		03774	09138
Ensembl ID		ENSG00000179094	ENSG00000049246
Uniprot IDs		O15534	A0A087WV69 A2I2N5 P56645
PDB IDs		1UL6
Enriched GO Terms of Interacting Partners?
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