LSM8 and EFTUD2

Number of citations of the paper that reports this interaction (PubMedID 22365833)
132

Data Source:
BioGRID (affinity chromatography technology, two hybrid)

		LSM8	EFTUD2
Description		LSM8 homolog, U6 small nuclear RNA associated	elongation factor Tu GTP binding domain containing 2
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GO Annotations	Cellular Component	Nucleus Nucleoplasm U6 SnRNP U4/U6 X U5 Tri-snRNP Complex U2-type Precatalytic Spliceosome Precatalytic Spliceosome Lsm2-8 Complex	Nucleus Nucleoplasm Cytosol Cajal Body Membrane Nuclear Speck Intracellular Membrane-bounded Organelle U4/U6 X U5 Tri-snRNP Complex U2-type Precatalytic Spliceosome U2-type Catalytic Step 2 Spliceosome Catalytic Step 2 Spliceosome Ribonucleoprotein Complex
	Molecular Function	RNA Binding Protein Binding U6 SnRNA Binding	RNA Binding GTPase Activity Protein Binding GTP Binding U5 SnRNA Binding
	Biological Process	MRNA Splicing, Via Spliceosome RNA Metabolic Process	MRNA Splicing, Via Spliceosome Cellular Response To Drug Response To Cocaine
Pathways		mRNA Splicing - Major Pathway	mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway
Drugs
Diseases
GWAS		Anti-thyroglobulin (TgAb) levels in Hashimoto's thyroiditis ( 30926877) Anti-thyroid peroxidase (TPOAb) and anti-thyroglobulin (TgAb) levels in Hashimoto's thyroiditis ( 30926877) Glaucoma (primary open-angle) ( 29891935) Intraocular pressure ( 29617998) Plasma anti-thyroid peroxidase levels ( 29678681) Positive urgency ( 30718321) Response to methotrexate in juvenile idiopathic arthritis ( 24709693) Triglyceride levels ( 30108155)	Asthma ( 31619474) Craniofacial microsomia ( 26853712)
Interacting Genes		49 interacting genes: ARNT BCKDK COL23A1 DBF4 DCP1A DCP1B DPAGT1 ECHDC2 EFTUD2 EXOSC10 EXOSC6 FERMT3 GMPPA GTF2I HSPA9 IFNLR1 IGHMBP2 ISOC2 ITSN2 KCTD3 LSM2 LSM3 LSM5 LSM6 LSM7 MAPK8IP2 MGA MINDY1 MPRIP MRPL48 MTHFR NAGK NME4 PDCD2 PGD PHF11 RBM5 RPL24 RSC1A1 RSL24D1 SEPTIN10 SEPTIN5 SMU1 SNRNP200 SNRPB SNRPD1 TALDO1 THUMPD3 UPF1	12 interacting genes: ARPC3 CYFIP1 GOLM1 GSK3B HINFP LSM8 PIN1 SF3B3 SF3B4 SNRNP200 SREK1 WBP4
Entrez ID		51691	9343
HPRD ID		06288	04869
Ensembl ID		ENSG00000128534	ENSG00000108883
Uniprot IDs		A4D0W0 O95777	B3KX19 Q15029
PDB IDs		3JCR 5O9Z 6AH0 6AHD 6QW6 6QX9	3JCR 5MQF 5O9Z 5XJC 5YZG 5Z56 5Z57 5Z58 6AH0 6AHD 6FF4 6FF7 6ICZ 6ID0 6ID1 6QDV 6QW6 6QX9
Enriched GO Terms of Interacting Partners?
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