PPHLN1 and CCDC57

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

		PPHLN1	CCDC57
Description		periphilin 1	coiled-coil domain containing 57
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Chromosome Golgi Apparatus Cytosol
	Molecular Function	RNA Binding Protein Binding	Protein Binding
	Biological Process	Keratinization Negative Regulation Of Gene Expression, Epigenetic Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Methylation-dependent Chromatin Silencing Protein Localization To Heterochromatin
Pathways
Drugs
Diseases
GWAS		Coronary artery disease ( 29212778) Diastolic blood pressure ( 30224653)	Blood metabolite levels ( 24816252) Blood urea nitrogen levels ( 31152163) Proteinuria and chronic kidney disease ( 26420894)
Interacting Genes		24 interacting genes: APP BCL2L1 BRCA1 CASP5 CCDC57 CDC37 CDK6 CLK1 FBXO7 MTUS2 NAGK PAXIP1 PPL SEPTIN8 SNCAIP SQSTM1 SRPK2 TGM2 TOMM20 TOPBP1 TP53BP2 TSGA10 UFD1 VIM	46 interacting genes: AQP1 ARL4A AXIN1 CBX8 CCDC120 CDC20B CEP57L1 CWF19L2 ECPAS FAM161A FAM50B FAM90A1 GPKOW HAUS1 HBA2 LENG1 LINC00526 MFAP1 NAPRT NELFE NUMA1 PER1 PPHLN1 PPP1R18 PRAM1 PRPF31 PRR3 PTPN7 RAB3IL1 RNF6 ROBO3 RXRB SFI1 SIRPA TBC1D22B TLE5 TMEM100 TSGA10IP USP15 USP2 UTP14C ZFC3H1 ZGPAT ZMAT2 ZNF417 ZNF688
Entrez ID		51535	284001
HPRD ID		10488	14150
Ensembl ID		ENSG00000134283	ENSG00000176155
Uniprot IDs		Q8NEY8	A0A590UJT6 Q2TAC2
PDB IDs
Enriched GO Terms of Interacting Partners?
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