VGLL1 and TEAD1

Number of citations of the paper that reports this interaction (PubMedID 10518497)
36

Data Source:
HPRD (in vivo, two hybrid, in vitro)

		VGLL1	TEAD1
Description		vestigial like family member 1	TEA domain transcription factor 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm	Nuclear Chromatin Nucleus Nucleoplasm Transcription Factor Complex TEAD-1-YAP Complex
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Transcription Coactivator Activity	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Proximal Promoter Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Binding Transcription Coactivator Binding DNA Binding DNA-binding Transcription Factor Activity Transcription Coregulator Activity Protein Binding Sequence-specific DNA Binding Transcription Regulatory Region DNA Binding Protein Heterodimerization Activity
	Biological Process	Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Nucleic Acid-templated Transcription	Transcription Initiation From RNA Polymerase II Promoter Hippo Signaling Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Embryonic Organ Development Protein-containing Complex Assembly Positive Regulation Of Pri-miRNA Transcription By RNA Polymerase II
Pathways			YAP1- and WWTR1 (TAZ)-stimulated gene expression RUNX3 regulates YAP1-mediated transcription EGR2 and SOX10-mediated initiation of Schwann cell myelination
Drugs
Diseases
GWAS			Central retinal vein equivalent ( 26567291) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Diisocyanate-induced asthma ( 25918132) HDL cholesterol levels x loop diuretics use interaction ( 31806883) Heel bone mineral density ( 30598549) Height ( 28552196 20881960 25282103) Household income (MTAG) ( 31844048) Intelligence (MTAG) ( 29326435)
Interacting Genes		4 interacting genes: TEAD1 TEAD2 TEAD3 TEAD4	17 interacting genes: BORCS8-MEF2B GCAT HLA-DMB INSR MAX MEF2A MEF2C MYH7 NCOA1 SRF TBP UBTD1 VGLL1 VGLL2 VGLL4 YAP1 ZDHHC17
Entrez ID		51442	7003
HPRD ID		06751	01802
Ensembl ID		ENSG00000102243	ENSG00000187079
Uniprot IDs		Q99990	P28347 Q59EF3
PDB IDs			2HZD 3KYS 4RE1 4Z8E 5NNX 6HIL 6IM5
Enriched GO Terms of Interacting Partners?
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