TEAD1 and BORCS8-MEF2B

Number of citations of the paper that reports this interaction (PubMedID 12861002)
28

Data Source:
HPRD (in vitro)

		TEAD1	BORCS8-MEF2B
Description		TEA domain transcription factor 1	BORCS8-MEF2B readthrough
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GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm Transcription Factor Complex TEAD-1-YAP Complex	Nuclear Chromatin Nucleus Nucleoplasm Transcription Factor Complex Cytosol Cell Junction
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Proximal Promoter Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Binding Transcription Coactivator Binding DNA Binding DNA-binding Transcription Factor Activity Transcription Coregulator Activity Protein Binding Sequence-specific DNA Binding Transcription Regulatory Region DNA Binding Protein Heterodimerization Activity	Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Transcription Factor Binding Histone Deacetylase Binding Sequence-specific DNA Binding Transcription Regulatory Region DNA Binding Protein Dimerization Activity
	Biological Process	Transcription Initiation From RNA Polymerase II Promoter Hippo Signaling Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Embryonic Organ Development Protein-containing Complex Assembly Positive Regulation Of Pri-miRNA Transcription By RNA Polymerase II	Multicellular Organism Development Muscle Organ Development Positive Regulation Of Transcription By RNA Polymerase II
Pathways		YAP1- and WWTR1 (TAZ)-stimulated gene expression RUNX3 regulates YAP1-mediated transcription EGR2 and SOX10-mediated initiation of Schwann cell myelination	Myogenesis
Drugs
Diseases
GWAS		Central retinal vein equivalent ( 26567291) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Diisocyanate-induced asthma ( 25918132) HDL cholesterol levels x loop diuretics use interaction ( 31806883) Heel bone mineral density ( 30598549) Height ( 28552196 20881960 25282103) Household income (MTAG) ( 31844048) Intelligence (MTAG) ( 29326435)	Height ( 28552196)
Interacting Genes		17 interacting genes: BORCS8-MEF2B GCAT HLA-DMB INSR MAX MEF2A MEF2C MYH7 NCOA1 SRF TBP UBTD1 VGLL1 VGLL2 VGLL4 YAP1 ZDHHC17	4 interacting genes: CABIN1 GDF15 TEAD1 TEX11
Entrez ID		7003	4207
HPRD ID		01802	02808
Ensembl ID		ENSG00000187079	ENSG00000213999
Uniprot IDs		P28347 Q59EF3	A0A024R7N0 Q02080
PDB IDs		2HZD 3KYS 4RE1 4Z8E 5NNX 6HIL 6IM5	1N6J 1TQE 6BYY 6BZ1 6C9L
Enriched GO Terms of Interacting Partners?
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